| Reaction Details |
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 | Report a problem with these data |
| Target | Gag-Pol polyprotein [489-587] |
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| Ligand | BDBM50121512 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_158026 (CHEMBL768619) |
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| Ki | 5000±n/a nM |
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| Kd | 309000±n/a nM |
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| KON | 172 M-1s-1 |
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| Citation |  Markgren, PO; Schaal, W; Hämäläinen, M; Karlén, A; Hallberg, A; Samuelsson, B; Danielson, UH Relationships between structure and interaction kinetics for HIV-1 protease inhibitors. J Med Chem45:5430-9 (2002) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Gag-Pol polyprotein [489-587] |
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| Name: | Gag-Pol polyprotein [489-587] |
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| Synonyms: | Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol |
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| Type: | Enzyme Subunit |
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| Mol. Mass.: | 10781.16 |
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| Organism: | Human immunodeficiency virus type 1 |
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| Description: | P04585[489-587] |
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| Residue: | 99 |
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| Sequence: | PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
|
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| BDBM50121512 |
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| n/a |
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| Name | BDBM50121512 |
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| Synonyms: | 2-[(2,5-Bis-benzyloxy-5-{[1-carboxy-2-(4-hydroxy-phenyl)-ethyl]-methyl-carbamoyl}-3,4-dihydroxy-pentanoyl)-methyl-amino]-3-(4-hydroxy-phenyl)-propionic acid | CHEMBL356211 |
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| Type | Small organic molecule |
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| Emp. Form. | C40H44N2O12 |
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| Mol. Mass. | 744.7836 |
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| SMILES | CN(C(Cc1ccc(O)cc1)C(O)=O)C(=O)[C@H](OCc1ccccc1)[C@H](O)[C@@H](O)[C@@H](OCc1ccccc1)C(=O)N(C)C(Cc1ccc(O)cc1)C(O)=O |
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| Structure | 
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