| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Neuronal acetylcholine receptor subunit beta-4 |
|---|
| Ligand | BDBM50110260 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_143393 (CHEMBL750860) |
|---|
| Ki | 6.2±n/a nM |
|---|
| Citation |  Gohlke, H; Gündisch, D; Schwarz, S; Seitz, G; Tilotta, MC; Wegge, T Synthesis and nicotinic binding studies on enantiopure diazine analogues of the novel (2-chloro-5-pyridyl)-9-azabicyclo[4.2.1]non-2-ene UB-165. J Med Chem45:1064-72 (2002) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Neuronal acetylcholine receptor subunit beta-4 |
|---|
| Name: | Neuronal acetylcholine receptor subunit beta-4 |
|---|
| Synonyms: | ACHB4_RAT | Acrb4 | Chrnb4 | N-alpha 2 | Neuronal acetylcholine receptor non-alpha-2
chain | Neuronal acetylcholine receptor protein beta-4 subunit |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 55863.89 |
|---|
| Organism: | Rattus norvegicus (Rat) |
|---|
| Description: | P12392 |
|---|
| Residue: | 495 |
|---|
| Sequence: | MRGTPLLLVSLFSLLQDGDCRLANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIRLELS
LSQLISVNEREQIMTTSIWLKQEWTDYRLAWNSSCYEGVNILRIPAKRVWLPDIVLYNNA
DGTYEVSVYTNVIVRSNGSIQWLPPAIYKSACKIEVKHFPFDQQNCTLKFRSWTYDHTEI
DMVLKSPTAIMDDFTPSGEWDIVALPGRRTVNPQDPSYVDVTYDFIIKRKPLFYTINLII
PCVLITSLAILVFYLPSDCGEKMTLCISVLLALTFFLLLISKIVPPTSLDIPLIGKYLLF
TMVLVTFSIVTTVCVLNVHHRSPSTHTMASWVKECFLHKLPTFLFMKRPGLEVSLVRVPH
PSQLHLATADTAATSALGPTSPSNLYGSSMYFVNPVPAAPKSAVSSHTAGLPRDARLRSS
GRFREDLQEALEGVSFIAQHLESDDRDQSVIEDWKFVAMVVDRLFLWVFVFVCILGTMGL
FLPPLFQIHAPSKDS
|
|
|
|---|
| BDBM50110260 |
|---|
| n/a |
|---|
| Name | BDBM50110260 |
|---|
| Synonyms: | 2-Pyridin-3-yl-9-aza-bicyclo[4.2.1]non-2-ene | 2-Pyridin-3-yl-9-aza-bicyclo[4.2.1]non-2-ene(DUB-165) | CHEMBL274538 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C13H16N2 |
|---|
| Mol. Mass. | 200.2795 |
|---|
| SMILES | C1CC2N[C@H]1CCC=C2c1cccnc1 |c:8,THB:9:8:3:1.0| |
|---|
| Structure | 
|
|---|
Search and Browse
