| Reaction Details |
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 | Report a problem with these data |
| Target | Beta-2 adrenergic receptor |
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| Ligand | BDBM50122649 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_38606 (CHEMBL652289) |
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| IC50 | 520±n/a nM |
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| Citation |  Tanaka, N; Tamai, T; Mukaiyama, H; Hirabayashi, A; Muranaka, H; Ishikawa, T; Kobayashi, J; Akahane, S; Akahane, M Relationship between stereochemistry and the beta3-adrenoceptor agonistic activity of 4'-hydroxynorephedrine derivative as an agent for treatment of frequent urination and urinary incontinence. J Med Chem46:105-12 (2002) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Beta-2 adrenergic receptor |
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| Name: | Beta-2 adrenergic receptor |
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| Synonyms: | ADRB2_RAT | Adrb2 | Adrb2r | Adrenergic receptor beta |
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| Type: | PROTEIN |
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| Mol. Mass.: | 46896.26 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_38603 |
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| Residue: | 418 |
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| Sequence: | MEPHGNDSDFLLAPNGSRAPGHDITQERDEAWVVGMAILMSVIVLAIVFGNVLVITAIAK
FERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWNFGNFWCEFWTSIDVLCVTAS
IETLCVIAVDRYVAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHKQ
AIDCYAKETCCDFFTNQAYAIASSIVSFYVPLVVMVFVYSRVFQVAKRQLQKIDKSEGRF
HAQNLSQVEQDGRSGHGLRSSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIRA
NLIPKEVYILLNWLGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSSKTYGNGYSSNSNG
RTDYTGEQSAYQLGQEKENELLCEEAPGMEGFVNCQGTVPSLSIDSQGRNCNTNDSPL
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| BDBM50122649 |
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| n/a |
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| Name | BDBM50122649 |
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| Synonyms: | (2-Chloro-4-{2-[2-hydroxy-2-(4-hydroxy-phenyl)-1-methyl-ethylamino]-ethyl}-phenoxy)-acetic acid ethyl ester; hydrochloride | CHEMBL544427 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H26ClNO5 |
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| Mol. Mass. | 407.888 |
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| SMILES | CCOC(=O)COc1ccc(CCNC(C)C(O)c2ccc(O)cc2)cc1Cl |
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| Structure | 
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