| Reaction Details |
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 | Report a problem with these data |
| Target | Transporter |
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| Ligand | BDBM50127394 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_144981 (CHEMBL754323) |
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| IC50 | 1930±n/a nM |
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| Citation |  Carroll, FI 2002 Medicinal Chemistry Division Award address: monoamine transporters and opioid receptors. Targets for addiction therapy. J Med Chem46:1775-94 (2003) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Transporter |
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| Name: | Transporter |
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| Synonyms: | Monoamine transporters; Norepininephrine & dopamine | Norepinephrine Monoamine transporters |
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| Type: | PROTEIN |
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| Mol. Mass.: | 66787.87 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_1463061 |
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| Residue: | 597 |
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| Sequence: | MVTRTRETWGKKIDFLLSVVGFAVDLANVWRFPYLCYKNGGGAFLIPYTLFLIIAGMPLF
YMELALGQFNREGAATVWKICPFFKGVGYAVILIALYVGFYYNVIIAWSLYYLFASFTLN
LPWTNCGHAWNSPNCTDPKLLNASVLGDHTKYSKYKFTPAAEFYERGVLHLHESSGIHDI
GLPQWQLLLCLMVVIVVLYVSLWKGVKTSGKVVWITATLPYFVLFVLLVHGVTLPGASNG
INAYLHIDFYRLKEATVWIDAATQIFFSLGAGFGVLIAFASYNKFDNNCYRDALLTSTIN
CVTSFISGFAIFSILGYMAHEHKVKIEDVATEGAGLVFVLYPEAISTLSGSTFWAVLFFL
MLLALGLDSSMGGMEAVITGLADDFQVLKRHRKLFTCAVTLGTFLLAMFCITKGGIYVLT
LLDTFAAGTSILFAVLMEAIGVSWFYGVDRFSNDIQQMMGFKPGLYWRLCWKFVSPAFLL
FVVVVSIINFKPLTYDDYVYPPWANWVGWGIALSSMILVPAYVIYKFFSIRGSLWERVAY
GITPENEHHLLALEIELSSLQSFVITSCPIDPLLSSFLFISCQKTLVFKKSGPAPLI
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| BDBM50127394 |
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| n/a |
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| Name | BDBM50127394 |
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| Synonyms: | 8-Methyl-3-p-tolyl-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid isopropyl ester | CHEMBL298703 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H27NO2 |
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| Mol. Mass. | 301.4232 |
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| SMILES | CC(C)OC(=O)C1C2CC[C@H](C[C@@H]1c1ccc(C)cc1)N2C |THB:4:6:20:8.9,13:12:20:8.9,21:20:6.12.11:8.9| |
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| Structure | 
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