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TargetThymidylate kinase
LigandBDBM1
Substrate/Competitorn/a
Meas. Tech.ChEMBL_208211
Ki 27000±n/a nM
Citation Vanheusden VMunier-Lehmann HFroeyen MDugué LHeyerick ADe Keukeleire DPochet SBusson RHerdewijn PVan Calenbergh S 3'-C-branched-chain-substituted nucleosides and nucleotides as potent inhibitors of Mycobacterium tuberculosis thymidine monophosphate kinase. J Med Chem 46:3811-21 (2003) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Thymidylate kinase
Name:Thymidylate kinase
Synonyms:TMPK | Thymidine monophosphate kinase | dTMP kinase
Type:PROTEIN
Mol. Mass.:22636.29
Organism:Mycobacterium tuberculosis
Description:ChEMBL_208218
Residue:214
Sequence:
MLIAIEGVDGAGKRTLVEKLSGAFRAAGRSVATLAFPRYGQSVAADIAAEALHGEHGDLA
SSVYAMATLFALDRAGAVHTIQGLCRGYDVVILDRYVASNAAYSAARLHENAAGKAAAWV
QRIEFARLGLPKPDWQVLLAVSAELAGERSRGRAQRDPGRARDNYERDAELQQRTGAVYA
ELAAQGWGGRWLVVGADVDPGRLAATLAPPDVPS
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  Blast E-value cutoff:
BDBM1
n/a
NameBDBM1
Synonyms:BDBM233149 | thymidine
TypeNucleoside or nucleotide
Emp. Form.C6H10N6O
Mol. Mass.182.1832
SMILESCN(C)N\N=C1\N=CN=C1C(N)=O |c:6,8|
Structure
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