| Reaction Details |
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 | Report a problem with these data |
| Target | Histone deacetylase 2b |
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| Ligand | BDBM50134801 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_87879 (CHEMBL698798) |
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| IC50 | 25200±n/a nM |
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| Citation |  Mai, A; Massa, S; Pezzi, R; Rotili, D; Loidl, P; Brosch, G Discovery of (aryloxopropenyl)pyrrolyl hydroxyamides as selective inhibitors of class IIa histone deacetylase homologue HD1-A. J Med Chem46:4826-9 (2003) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Histone deacetylase 2b |
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| Name: | Histone deacetylase 2b |
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| Synonyms: | Histone deacetylase HD2 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 30785.07 |
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| Organism: | Zea mays |
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| Description: | ChEMBL_87549 |
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| Residue: | 286 |
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| Sequence: | MEVGGQEVKPGATVSCKVGDGLVIHLSQAALGESKKASENAILSVNIDDKKLVLGTLSVE
KHPQISCDLVFDKDFELPHNSKTRSVFFRGYKSPVPLFESNSGEDSSDEELKTDQIPLQN
NEIKISAAKVPAKDDDDDVFIILAMMMMIYSSDDDDDDFTTSDSDNEMSEEDDSSDEDEM
SEEDDSSDEDEMSGGADPSDDSSDESGSEHTSAPKKTDVVVGKKRAIKAEAPYGKKAKSE
QSSQKTGDKASTSHPAKQSIKTPADKSRKTPTADKKSPKSGSHGCK
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| BDBM50134801 |
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| n/a |
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| Name | BDBM50134801 |
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| Synonyms: | (E)-3-{4-[(E)-3-(4-Chloro-phenyl)-3-oxo-propenyl]-1-methyl-1H-pyrrol-2-yl}-N-hydroxy-acrylamide | (E)-3-{4-[3-(4-Chloro-phenyl)-3-oxo-propenyl]-1-methyl-1H-pyrrol-2-yl}-N-hydroxy-acrylamide | 3-(4-(3-(4-chlorophenyl)-3-oxoprop-1-enyl)-1-methyl-1H-pyrrol-2-yl)-N-hydroxyacrylamide | CHEMBL145531 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H15ClN2O3 |
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| Mol. Mass. | 330.766 |
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| SMILES | Cn1cc(\C=C\C(=O)c2ccc(Cl)cc2)cc1\C=C\C(=O)NO |
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| Structure | 
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