| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Somatostatin receptor type 4 |
|---|
| Ligand | BDBM50136784 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_200835 (CHEMBL873241) |
|---|
| IC50 | 1.2±n/a nM |
|---|
| Citation |  Erchegyi, J; Penke, B; Simon, L; Michaelson, S; Wenger, S; Waser, B; Cescato, R; Schaer, JC; Reubi, JC; Rivier, J Novel sst(4)-selective somatostatin (SRIF) agonists. 2. Analogues with beta-methyl-3-(2-naphthyl)alanine substitutions at position 8. J Med Chem46:5587-96 (2003) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Somatostatin receptor type 4 |
|---|
| Name: | Somatostatin receptor type 4 |
|---|
| Synonyms: | SOMATOSTATIN SST4 | SS-4-R | SS4-R | SS4R | SSR4_HUMAN | SST4R | SSTR4 | Somatostatin receptor type 4 (SSTR4) |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 42015.38 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P31391 |
|---|
| Residue: | 388 |
|---|
| Sequence: | MSAPSTLPPGGEEGLGTAWPSAANASSAPAEAEEAVAGPGDARAAGMVAIQCIYALVCLV
GLVGNALVIFVILRYAKMKTATNIYLLNLAVADELFMLSVPFVASSAALRHWPFGSVLCR
AVLSVDGLNMFTSVFCLTVLSVDRYVAVVHPLRAATYRRPSVAKLINLGVWLASLLVTLP
IAIFADTRPARGGQAVACNLQWPHPAWSAVFVVYTFLLGFLLPVLAIGLCYLLIVGKMRA
VALRAGWQQRRRSEKKITRLVLMVVVVFVLCWMPFYVVQLLNLFVTSLDATVNHVSLILS
YANSCANPILYGFLSDNFRRFFQRVLCLRCCLLEGAGGAEEEPLDYYATALKSKGGAGCM
CPPLPCQQEALQPEPGRKRIPLTRTTTF
|
|
|
|---|
| BDBM50136784 |
|---|
| n/a |
|---|
| Name | BDBM50136784 |
|---|
| Synonyms: | 6-amino-18-(4-aminobutyl)-9,24-dibenzyl-12-(4-hydroxybenzyl)-21-(1-hydroxyethyl)-15-(1-naphthylmethyl)-7,10,13,16,19,22,25-heptaoxo-3,4-dithia-8,11,14,17,20,23,26-heptaazacyclohexacosane-1-carboxylic acid | CHEMBL414916 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C56H67N9O11S2 |
|---|
| Mol. Mass. | 1106.315 |
|---|
| SMILES | C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)C(Cc2cccc3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@@H](N)CSSC[C@@H](NC(=O)[C@H](Cc2ccccc2)NC1=O)C(O)=O |
|---|
| Structure | 
|
|---|
Search and Browse
