| Reaction Details |
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 | Report a problem with these data |
| Target | D(2) dopamine receptor |
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| Ligand | BDBM82519 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_62085 (CHEMBL672457) |
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| Ki | >1000±n/a nM |
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| Citation |  Hirokawa, Y; Fujiwara, I; Suzuki, K; Harada, H; Yoshikawa, T; Yoshida, N; Kato, S Synthesis and structure-affinity relationships of novel N-(1-ethyl-4-methylhexahydro-1,4-diazepin-6-yl)pyridine-3-carboxamides with potent serotonin 5-HT3 and dopamine D2 receptor antagonistic activity. J Med Chem46:702-15 (2003) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| D(2) dopamine receptor |
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| Name: | D(2) dopamine receptor |
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| Synonyms: | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2_RAT | Dopamine D2 receptor | Dopamine2-like | Drd2 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 50931.60 |
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| Organism: | Rattus norvegicus (rat) |
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| Description: | P61169 |
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| Residue: | 444 |
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| Sequence: | MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVS
REKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTA
SILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQN
ECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPL
KGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPP
SHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMS
RRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNS
AVNPIIYTTFNIEFRKAFMKILHC
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| BDBM82519 |
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| n/a |
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| Name | BDBM82519 |
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| Synonyms: | 4-amino-5-chloro-2-methoxy-N-(8-methyl-8-azabicyclo[3.2.1]octan-3-yl)benzamide | BRL 24682 | CAS_76272-78-1 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H22ClN3O2 |
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| Mol. Mass. | 323.818 |
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| SMILES | [H]C12CCC([H])(CC(C1)NC(=O)c1cc(Cl)c(N)cc1OC)N2C |
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| Structure | 
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