| Reaction Details |
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 | Report a problem with these data |
| Target | Growth hormone secretagogue receptor type 1 |
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| Ligand | BDBM50125891 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_72519 (CHEMBL685784) |
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| IC50 | 167±n/a nM |
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| Citation |  Guerlavais, V; Boeglin, D; Mousseaux, D; Oiry, C; Heitz, A; Deghenghi, R; Locatelli, V; Torsello, A; Ghé, C; Catapano, F; Muccioli, G; Galleyrand, JC; Fehrentz, JA; Martinez, J New active series of growth hormone secretagogues. J Med Chem46:1191-203 (2003) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Growth hormone secretagogue receptor type 1 |
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| Name: | Growth hormone secretagogue receptor type 1 |
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| Synonyms: | GH-releasing peptide receptor | GHRP | GHS-R | GHSR | GHSR_HUMAN | Ghrelin Receptor (Growth Hormone Secretagogue Receptor Type 1) | Ghrelin receptor | Ghrelin receptor 1a (GHS-R1a) |
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| Type: | Receptor |
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| Mol. Mass.: | 41334.57 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Receptor binding studies use plasma membranes from LLC PK-1 cells transiently transfected with hGHSR1a. |
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| Residue: | 366 |
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| Sequence: | MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAG
NLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQ
FVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFV
LVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLW
RRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQI
SQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWT
ESSINT
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| BDBM50125891 |
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| n/a |
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| Name | BDBM50125891 |
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| Synonyms: | CHEMBL18853 | N-{2-(1H-Indol-3-yl)-1-[(R)-(R)-2-(1H-indol-3-yl)-1-propionylamino-ethylcarbamoyl]-ethyl}-2-methyl-2-methylamino-propionamide |
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| Type | Small organic molecule |
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| Emp. Form. | C29H36N6O3 |
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| Mol. Mass. | 516.6345 |
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| SMILES | CCC(=O)N[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)C(C)(C)NC |
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| Structure | 
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