| Reaction Details |
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 | Report a problem with these data |
| Target | Plasmepsin II |
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| Ligand | BDBM50146773 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_154918 (CHEMBL764692) |
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| Ki | 600±n/a nM |
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| Citation |  Fontaine, F; Pastor, M; Sanz, F Incorporating molecular shape into the alignment-free Grid-Independent Descriptors. J Med Chem47:2805-15 (2004) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Plasmepsin II |
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| Name: | Plasmepsin II |
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| Synonyms: | Aspartic hemoglobinase II | PFAPD | PLM2_PLAFX | PMII | Plasmepsin 2 | Plasmepsin 2 (PM-II) | Plasmepsin-II |
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| Type: | Enzyme |
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| Mol. Mass.: | 51482.09 |
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| Organism: | Plasmodium falciparum |
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| Description: | P46925 |
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| Residue: | 453 |
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| Sequence: | MDITVREHDFKHGFIKSNSTFDGLNIDNSKNKKKIQKGFQILYVLLFCSVMCGLFYYVYE
NVWLQRDNEMNEILKNSEHLTIGFKVENAHDRILKTIKTHKLKNYIKESVNFLNSGLTKT
NYLGSSNDNIELVDFQNIMFYGDAEVGDNQQPFTFILDTGSANLWVPSVKCTTAGCLTKH
LYDSSKSRTYEKDGTKVEMNYVSGTVSGFFSKDLVTVGNLSLPYKFIEVIDTNGFEPTYT
ASTFDGILGLGWKDLSIGSVDPIVVELKNQNKIENALFTFYLPVHDKHTGFLTIGGIEER
FYEGPLTYEKLNHDLYWQITLDAHVGNIMLEKANCIVDSGTSAITVPTDFLNKMLQNLDV
IKVPFLPFYVTLCNNSKLPTFEFTSENGKYTLEPEYYLQHIEDVGPGLCMLNIIGLDFPV
PTFILGDPFMRKYFTVFDYDNHSVGIALAKKNL
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| BDBM50146773 |
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| n/a |
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| Name | BDBM50146773 |
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| Synonyms: | 1-[(1-{1-[1-Hydroxy-2-(3-phenyl-propylcarbamoyl)-ethyl]-3-methyl-butylcarbamoyl}-2-methyl-butylcarbamoyl)-methyl]-4-phenyl-piperidine-4-carboxylic acid amide | CHEMBL317098 |
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| Type | Small organic molecule |
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| Emp. Form. | C37H55N5O5 |
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| Mol. Mass. | 649.8631 |
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| SMILES | CCC(C)C(NC(=O)CN1CCC(CC1)(C(N)=O)c1ccccc1)C(=O)NC(CC(C)C)C(O)CC(=O)NCCCc1ccccc1 |
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| Structure | 
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