| Reaction Details |
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 | Report a problem with these data |
| Target | Glycogen phosphorylase, liver form |
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| Ligand | BDBM50065965 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_70994 (CHEMBL680570) |
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| IC50 | 130±n/a nM |
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| Citation |  Erlanson, DA; McDowell, RS; O'Brien, T Fragment-based drug discovery. J Med Chem47:3463-82 (2004) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Glycogen phosphorylase, liver form |
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| Name: | Glycogen phosphorylase, liver form |
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| Synonyms: | Glycogen phosphorylase, liver form | Liver glycogen phosphorylase | PYGL_MOUSE | Pygl |
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| Type: | PROTEIN |
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| Mol. Mass.: | 97468.48 |
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| Organism: | Mus musculus |
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| Description: | ChEMBL_70994 |
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| Residue: | 850 |
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| Sequence: | MAKPLTDQEKRRQISIRGIVGVENVAELKKGFNRHLHFTLVKDRNVATPRDYYFALAHTV
RDHLVGRWIRTQQHYYDKCPKRVYYLSLEFYMGRTLQNTMINLGLQNACDEAIYQLGLDM
EELEEIEEDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEYGIFNQKIREGWQVEEA
DDWLRHGNPWEKARPEFMLPVHFYGRVEHTQTGTKWVDTQVVLALPYDTPVPGYMNNTVN
TMRLWSARAPNDFNLQDFNVGDYIQAVLDRNLAENISRVLYPNDNFFEGKELRLKQEYFV
VAATLQDVIRRFKASKFGSKDGMGTVFDAFPDQVAIQLNDTHPALAIPELMRIFVDIEKL
PWAKAWEITKKTFAYTNHTVLPEALERWPVELVEKLLPRHLEIIYEINQKHLDRIVALFP
KDISRMRRMSLIEEEGGKRINMAHLCIVGCHAVNGVAKIHSDIVKTQVFKDFSELEPDKF
QNKTNGITPRRWLLLCNPGLADLIAEKIGEDYVKDLSQLTKLHSFVSDDIFLREIAKVKQ
ENKLKFSQFLEKEYKVKINPSSMFDVHVKRIHEYKRQLLNCLHVITMYNRIKKDPKKFFV
PRTVIIGGKAAPGYHMAKMIIKLITSVAEVVNNDPMVGSKLKVIFLENYRVSLAEKVIPA
TDLSEQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGEENLFIFGMRVDDVA
ALDKKGYEAKEYYEALPELKLVIDQIDNGFFSPNQPDLFKDIINMLFYHDRFKVFADYEA
YVKCQEKVSQLYMNQKAWNTMVLKNIAASGKFSSDRTIKEYAKDIWNMEPSDLKISLSNE
SSNGVSANGK
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| BDBM50065965 |
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| n/a |
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| Name | BDBM50065965 |
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| Synonyms: | 5-Chloro-1H-indole-2-carboxylic acid ((1S,2R)-1-benzyl-2-dimethylcarbamoyl-2-hydroxy-ethyl)-amide | 5-Chloro-1H-indole-2-carboxylic acid [2-((R)-dimethyl-carbamoyl)-2-hydroxy-1-((S)-phenylmethyl)-ethyl]-amide | CHEMBL319136 | CP-91149 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H22ClN3O3 |
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| Mol. Mass. | 399.871 |
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| SMILES | CN(C)C(=O)[C@H](O)[C@H](Cc1ccccc1)NC(=O)c1cc2cc(Cl)ccc2[nH]1 |
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| Structure | 
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