| Reaction Details |
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 | Report a problem with these data |
| Target | Tyrosine-protein phosphatase non-receptor type 1 |
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| Ligand | BDBM13971 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_162588 (CHEMBL768529) |
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| Ki | 1200±n/a nM |
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| Citation |  Erlanson, DA; McDowell, RS; O'Brien, T Fragment-based drug discovery. J Med Chem47:3463-82 (2004) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Tyrosine-protein phosphatase non-receptor type 1 |
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| Name: | Tyrosine-protein phosphatase non-receptor type 1 |
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| Synonyms: | PTN1_HUMAN | PTP1B | PTPN1 | Protein tyrosine phosphatase 1B (PTP1B) | Protein tyrosine phosphatase-1B (PTP1B) | Protein-tyrosine phosphatase 1B | Protein-tyrosine phosphatase 1B (PTP1B) | Tyrosine-protein phosphatase non-receptor type 1 | Tyrosine-protein phosphatase non-receptor type 1 (PTP1B) |
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| Type: | Protein phosphatase |
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| Mol. Mass.: | 49963.76 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Human recombinant GST-fusion PTP1B (1-435). |
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| Residue: | 435 |
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| Sequence: | MEMEKEFEQIDKSGSWAAIYQDIRHEASDFPCRVAKLPKNKNRNRYRDVSPFDHSRIKLH
QEDNDYINASLIKMEEAQRSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRVMEKGSLK
CAQYWPQKEEKEMIFEDTNLKLTLISEDIKSYYTVRQLELENLTTQETREILHFHYTTWP
DFGVPESPASFLNFLFKVRESGSLSPEHGPVVVHCSAGIGRSGTFCLADTCLLLMDKRKD
PSSVDIKKVLLEMRKFRMGLIQTADQLRFSYLAVIEGAKFIMGDSSVQDQWKELSHEDLE
PPPEHIPPPPRPPKRILEPHNGKCREFFPNHQWVKEETQEDKDCPIKEEKGSPLNAAPYG
IESMSQDTEVRSRVVGGSLRGAQAASPAKGEPSLPEKDEDHALSYWKPFLVNMCVATVLT
AGAYLCYRFLFNSNT
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| BDBM13971 |
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| n/a |
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| Name | BDBM13971 |
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| Synonyms: | 1:1 racemic mixture | 2-({4-[2-acetamido-2-(pentylcarbamoyl)ethyl]-2-ethylphenyl}amidoformic acid)benzoic acid | 2-{[4-(2-Acetylamino-2-pentylcarbamoylethyl)-2-ethylphenyl]oxalylamino}benzoic Acid | CHEMBL55799 | Oxalylarylaminobenzoic Acid Analog 12b | oxalyl-aryl-amino benzoic acid-based inhibitor 2 |
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| Type | Small organic molecule |
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| Emp. Form. | C27H33N3O7 |
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| Mol. Mass. | 511.5668 |
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| SMILES | CCCCCNC(=O)C(Cc1ccc(N(C(=O)C(O)=O)c2ccccc2C(O)=O)c(CC)c1)NC(C)=O |
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| Structure | 
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