| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A1 |
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| Ligand | BDBM50149356 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_29111 (CHEMBL638723) |
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| Ki | 31±n/a nM |
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| Citation |  Colotta, V; Catarzi, D; Varano, F; Calabri, FR; Lenzi, O; Filacchioni, G; Martini, C; Trincavelli, L; Deflorian, F; Moro, S 1,2,4-triazolo[4,3-a]quinoxalin-1-one moiety as an attractive scaffold to develop new potent and selective human A3 adenosine receptor antagonists: synthesis, pharmacological, and ligand-receptor modeling studies. J Med Chem47:3580-90 (2004) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A1 |
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| Name: | Adenosine receptor A1 |
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| Synonyms: | AA1R_BOVIN | ADENOSINE A1 | ADENOSINE A1 high | ADENOSINE A1 low | ADORA1 | Adenosine A1 receptor |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 36602.99 |
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| Organism: | BOVINE |
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| Description: | ADENOSINE 0 BOVINE::P28190 |
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| Residue: | 326 |
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| Sequence: | MPPSISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGA
LVIPLAILINIGPRTYFHTCLKVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVT
PRRAVVAITGCWILSFVVGLTPMFGWNNLSAVERDWLANGSVGEPVIECQFEKVISMEYM
VYFNFFVWVLPPLLLMVLIYMEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALIL
FLFALSWLPLHILNCITLFCPSCHMPRILIYIAIFLSHGNSAMNPIVYAFRIQKFRVTFL
KIWNDHFRCQPAPPVDEDAPAERPDD
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| BDBM50149356 |
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| n/a |
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| Name | BDBM50149356 |
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| Synonyms: | 2-(4-Hydroxy-phenyl)-2H,5H-[1,2,4]triazolo[4,3-a]quinoxaline-1,4-dione | CHEMBL332969 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H10N4O3 |
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| Mol. Mass. | 294.2649 |
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| SMILES | Oc1ccc(cc1)-n1nc2n(c3ccccc3[nH]c2=O)c1=O |
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| Structure | 
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