| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Sterol O-acyltransferase 1 |
|---|
| Ligand | BDBM50150483 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_306084 (CHEMBL833585) |
|---|
| IC50 | 150000±n/a nM |
|---|
| Citation |  Xu, MZ; Lee, WS; Kim, MJ; Park, DS; Yu, H; Tian, GR; Jeong, TS; Park, HY Acyl-CoA: cholesterol acyltransferase inhibitory activities of fatty acid amides isolated from Mylabris phalerate Pallas. Bioorg Med Chem Lett14:4277-80 (2004) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Sterol O-acyltransferase 1 |
|---|
| Name: | Sterol O-acyltransferase 1 |
|---|
| Synonyms: | ACAT-1 | Acact | Acat | Cholesterol acyltransferase 1 | SOAT1_RAT | Soat1 | Sterol O-acyltransferase, Soat |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 64165.56 |
|---|
| Organism: | Rattus norvegicus |
|---|
| Description: | ChEMBL_28796 |
|---|
| Residue: | 545 |
|---|
| Sequence: | MVGEETSLRNRLSRSAENPEQDEAQKNLLDTHRNGHITMKQLIAKKRQLAAEAEELKPLF
LKEVGCHFDDFVTNLIDKSASLDNGGCALTTFSILEEMKNNHRAKDLRAPPEQGKIFISR
RSLLDELFEVDHIRTIYHMFIALLIIFILSTLVVDYIDEGRLVLEFSLLAYAFGQFPIVI
WTWWAMFLSTLAIPYFLFQRWAHGYSKSSHPLIYSLIHGAFFLVFQLGILGFIPTYVVLA
YTLPPASRFILILEQIRLVMKAHSYVRENVPRVLSAAKEKSSTVPVPTVNQYLYFLFAPT
LIYRDSYPRTPTVRWGYVAMQFLQVFGCLFYVYYIFERLCAPLFRNIKQEPFSARVLVLC
VFNSILPGVLMLFLSFFAFLHCWLNAFAEMLRFGDRMFYKDWWNSTSYSNYYRTWNVVVH
DWLYYYVYKDLLWFFSKRFRPAAMLAVFALSAVVHEYALAVCLSYFYPVLFVLFMFFGMA
FNFIVNDSRKRPVWNIMVRASLFLGHGVILCFYSQEWYARQRCPLKNPTFLDYVRPRTWT
CRYVF
|
|
|
|---|
| BDBM50150483 |
|---|
| n/a |
|---|
| Name | BDBM50150483 |
|---|
| Synonyms: | (9Z,12Z)-Octadeca-9,12-dienoic acid amide | CHEMBL64122 | Octadeca-9,12-dienoic acid amide |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C18H33NO |
|---|
| Mol. Mass. | 279.4607 |
|---|
| SMILES | CCCCC\C=C/C\C=C/CCCCCCCC(N)=O |
|---|
| Structure | 
|
|---|
Search and Browse
