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TargetProstanoid EP4 Receptor
LigandBDBM17638
Substrate/Competitorn/a
Meas. Tech.ChEMBL_302498
Ki>10000±n/a nM
Citation Torisu KKobayashi KIwahashi MEgashira HNakai YOkada YNanbu FOhuchida SNakai HToda M Discovery of new chemical leads for prostaglandin D2 receptor antagonists. Bioorg Med Chem Lett 14:4557-62 (2004) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Prostanoid EP4 Receptor
Name:Prostanoid EP4 receptor
Synonyms:PGE receptor, EP4 subtype
Type:G-protein coupled receptor
Mol. Mass.:56175.66
Organism:Mus musculus (Mouse)
Description:n/a
Residue:513
Sequence:
MAEVGGTIPRSNRELQRCVLLTTTIMSIPGVNASFSSTPERLNSPVTIPAVMFIFGVVGN
LVAIVVLCKSRKEQKETTFYTLVCGLAVTDLLGTLLVSPVTIATYMKGQWPGDQALCDYS
TFILLFFGLSGLSIICAMSIERYLAINHAYFYSHYVDKRLAGLTLFAIYASNVLFCALPN
MGLGRSERQYPGTWCFIDWTTNVTAYAAFSYMYAGFSSFLILATVLCNVLVCGALLRMHR
QFMRRTSLGTEQHHAAAAAAVASVACRGHAGASPALQRLSDFRRRRSFRRIAGAEIQMVI
LLIATSLVVLICSIPLVVRVFINQLYQPNVVKDISRNPDLQAIRIASVNPILDPWIYILL
RKTVLSKAIEKIKCLFCRIGGSGRDSSAQHCSESRRTSSAMSGHSRSFLARELKEISSTS
QTLLYLPDLTESSLGGRNLLPGSHGMGLTQADTTSLRTLRISETSDSSQGQDSESVLLVD
EVSGSHREEPASKGNSLQVTFPSETLKLSEKCI
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  Blast E-value cutoff:
BDBM17638
n/a
NameBDBM17638
Synonyms:2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl-1H-indol-3-yl}acetic acid | CHEMBL6 | Indocin | Indomethacin | US9271961, Indomethacin | indometacin
TypeSmall organic molecule
Emp. Form.C19H16ClNO4
Mol. Mass.357.788
SMILESCOc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(CC(O)=O)c2c1
Structure
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