| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Prostaglandin E2 receptor EP1 subtype |
|---|
| Ligand | BDBM50150966 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_302495 (CHEMBL828212) |
|---|
| Ki | 5200±n/a nM |
|---|
| Citation |  Torisu, K; Kobayashi, K; Iwahashi, M; Egashira, H; Nakai, Y; Okada, Y; Nanbu, F; Ohuchida, S; Nakai, H; Toda, M Discovery of new chemical leads for prostaglandin D2 receptor antagonists. Bioorg Med Chem Lett14:4557-62 (2004) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Prostaglandin E2 receptor EP1 subtype |
|---|
| Name: | Prostaglandin E2 receptor EP1 subtype |
|---|
| Synonyms: | PE2R1_MOUSE | PGE receptor, EP1 subtype | Prostaglandin E1 | Prostaglandin E2 receptor EP1 subtype | Prostanoid EP1 receptor | Ptger1 | Ptgerep1 |
|---|
| Type: | G-protein coupled receptor |
|---|
| Mol. Mass.: | 43000.62 |
|---|
| Organism: | Mus musculus (Mouse) |
|---|
| Description: | n/a |
|---|
| Residue: | 405 |
|---|
| Sequence: | MSPCGLNLSLADEAATCATPRLPNTSVVLPTGDNGTSPALPIFSMTLGAVSNVLALALLA
QVAGRMRRRRSAATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMV
FFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALAVLAAMALAVALLPLVHVGR
YELQYPGTWCFISLGPRGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRR
SRRFRKTAGPDDRRRWGSRGPRLASASSASSITSATATLRSSRGGGSARRVHAHDVEMVG
QLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQA
MLRQLLRLLPLRVSAKGGPTELGLTKSAWEASSLRSSRHSGFSHL
|
|
|
|---|
| BDBM50150966 |
|---|
| n/a |
|---|
| Name | BDBM50150966 |
|---|
| Synonyms: | CHEMBL182572 | [1-(4-Butoxy-benzoyl)-2-methyl-1H-indol-3-yl]-acetic acid |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C22H23NO4 |
|---|
| Mol. Mass. | 365.4223 |
|---|
| SMILES | CCCCOc1ccc(cc1)C(=O)n1c(C)c(CC(O)=O)c2ccccc12 |
|---|
| Structure | 
|
|---|
Search and Browse
