| Reaction Details |
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 | Report a problem with these data |
| Target | 1-deoxy-D-xylulose 5-phosphate reductoisomerase |
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| Ligand | BDBM50153710 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_303122 (CHEMBL829631) |
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| Ki | 120000±n/a nM |
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| Citation |  Phaosiri, C; Proteau, PJ Substrate analogs for the investigation of deoxyxylulose 5-phosphate reductoisomerase inhibition: synthesis and evaluation. Bioorg Med Chem Lett14:5309-12 (2004) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| 1-deoxy-D-xylulose 5-phosphate reductoisomerase |
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| Name: | 1-deoxy-D-xylulose 5-phosphate reductoisomerase |
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| Synonyms: | 1-Deoxy-D-xylulose 5-phosphate reductoisomerase (DXP) | 1-Deoxyxylulose 5-phosphate reductoisomerase (DXR) | 1-deoxy-D-xylulose 5-phosphate reductoisomerase (DXR) | 2-C-methyl-D-erythritol 4-phosphate synthase | DXP reductoisomerase | DXR_ECOLI | dxr | ispC | yaeM |
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| Type: | Protein |
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| Mol. Mass.: | 43384.52 |
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| Organism: | Escherichia coli |
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| Description: | P45568 |
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| Residue: | 398 |
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| Sequence: | MKQLTILGSTGSIGCSTLDVVRHNPEHFRVVALVAGKNVTRMVEQCLEFSPRYAVMDDEA
SAKLLKTMLQQQGSRTEVLSGQQAACDMAALEDVDQVMAAIVGAAGLLPTLAAIRAGKTI
LLANKESLVTCGRLFMDAVKQSKAQLLPVDSEHNAIFQSLPQPIQHNLGYADLEQNGVVS
ILLTGSGGPFRETPLRDLATMTPDQACRHPNWSMGRKISVDSATMMNKGLEYIEARWLFN
ASASQMEVLIHPQSVIHSMVRYQDGSVLAQLGEPDMRTPIAHTMAWPNRVNSGVKPLDFC
KLSALTFAAPDYDRYPCLKLAMEAFEQGQAATTALNAANEITVAAFLAQQIRFTDIAALN
LSVLEKMDMREPQCVDDVLSVDANAREVARKEVMRLAS
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| BDBM50153710 |
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| n/a |
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| Name | BDBM50153710 |
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| Synonyms: | 3S-hydroxypentan-2-one 5-phosphate |
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| Type | Small organic molecule |
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| Emp. Form. | C5H9O6P |
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| Mol. Mass. | 196.0962 |
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| SMILES | CC(=O)[C@@H](O)CCOP([O-])([O-])=O |
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| Structure | 
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