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TargetCarbonic anhydrase 1
LigandBDBM50160673
Substrate/Competitorn/a
Meas. Tech.ChEMBL_302341
Ki 6±n/a nM
Citation Vullo DVoipio JInnocenti ARivera CRanki HScozzafava AKaila KSupuran CT Carbonic anhydrase inhibitors. Inhibition of the human cytosolic isozyme VII with aromatic and heterocyclic sulfonamides. Bioorg Med Chem Lett 15:971-6 (2005) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Carbonic anhydrase 1
Name:Carbonic anhydrase
Synonyms:CA-I | CAB | Carbonate dehydratase I | Carbonic anhydrase 1 (CA I) | Carbonic anhydrase 1 (CA-I) | Carbonic anhydrase 1 (Recombinant CA I) | Carbonic anhydrase 2 (CA II) | Carbonic anhydrase B | Carbonic anhydrase I (CA I) | Carbonic anhydrase I (CA-I) | Carbonic anhydrase I (CAI) | Carbonic anhydrase I (hCA I) | Carbonic anhydrase isoenzyme I (hCA I) | hCA
Type:Enzyme
Mol. Mass.:28873.37
Organism:Homo sapiens (Human)
Description:P00915
Residue:261
Sequence:
MASPDWGYDDKNGPEQWSKLYPIANGNNQSPVDIKTSETKHDTSLKPISVSYNPATAKEI
INVGHSFHVNFEDNDNRSVLKGGPFSDSYRLFQFHFHWGSTNEHGSEHTVDGVKYSAELH
VAHWNSAKYSSLAEAASKADGLAVIGVLMKVGEANPKLQKVLDALQAIKTKGKRAPFTNF
DPSTLLPSSLDFWTYPGSLTHPPLYESVTWIICKESISVSSEQLAQFRSLLSNVEGDNAV
PMQHNNRPTQPLKGRTVRASF
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  Blast E-value cutoff:
BDBM50160673
n/a
NameBDBM50160673
Synonyms:5-(4-Amino-benzenesulfonylamino)-4,5-dihydro-[1,3,4]thiadiazole-2-sulfonic acid amide | CHEMBL427312
TypeSmall organic molecule
Emp. Form.C8H11N5O4S3
Mol. Mass.337.399
SMILESNc1ccc(cc1)S(=O)(=O)NC1=NNC(S1)S(N)(=O)=O |t:12|
Structure
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