| Reaction Details |
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 | Report a problem with these data |
| Target | Mu-type opioid receptor |
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| Ligand | BDBM50154209 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_303422 (CHEMBL840085) |
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| Ki | 40±n/a nM |
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| Citation |  Grundt, P; Williams, IA; Lewis, JW; Husbands, SM Identification of a new scaffold for opioid receptor antagonism based on the 2-amino-1,1-dimethyl-7-hydroxytetralin pharmacophore. J Med Chem47:5069-75 (2004) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Mu-type opioid receptor |
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| Name: | Mu-type opioid receptor |
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| Synonyms: | M-OR-1 | MOP | MOR-1 | MOR1 | MUOR1 | Mu Opioid Receptor | Mu opiate receptor | OPIATE Mu | OPRM1 | OPRM_HUMAN | hMOP | mu-type opioid receptor isoform MOR-1 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 44789.51 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P35372 |
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| Residue: | 400 |
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| Sequence: | MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCP
PTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALAT
STLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDF
RTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFI
FAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHI
YVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNI
EQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETAPLP
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| BDBM50154209 |
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| n/a |
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| Name | BDBM50154209 |
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| Synonyms: | 8,8-Dimethyl-7-[methyl-((E)-3-phenyl-allyl)-amino]-5,6,7,8-tetrahydro-naphthalen-2-ol | CHEMBL365483 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H27NO |
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| Mol. Mass. | 321.4559 |
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| SMILES | CN(C\C=C\c1ccccc1)C1CCc2ccc(O)cc2C1(C)C |
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| Structure | 
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