Reaction Details |
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Target | Gag-Pol polyprotein [489-587] |
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Ligand | BDBM50156149 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_302137 (CHEMBL841761) |
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Kd | 2990±n/a nM |
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Citation | Shuman, CF; Vrang, L; Danielson, UH Improved structure-activity relationship analysis of HIV-1 protease inhibitors using interaction kinetic data. J Med Chem47:5953-61 (2004) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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Gag-Pol polyprotein [489-587] |
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Name: | Gag-Pol polyprotein [489-587] |
Synonyms: | Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol |
Type: | Enzyme Subunit |
Mol. Mass.: | 10781.16 |
Organism: | Human immunodeficiency virus type 1 |
Description: | P04585[489-587] |
Residue: | 99 |
Sequence: | PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
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BDBM50156149 |
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n/a |
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Name | BDBM50156149 |
Synonyms: | (1R,2R,3S,4R)-1,4-bis({[(2S)-2,3-dimethylbutanoyl]carbamoyl})-2,3-dihydroxy-4-phenoxybutan-1-olate | 1,6-Bis-(2,3-dimethyl-butyrylamino)-3,4-dihydroxy-1,6-dioxo-5-phenoxy-hexan-2-ol anion |
Type | Small organic molecule |
Emp. Form. | C24H35N2O8 |
Mol. Mass. | 479.5438 |
SMILES | CC(C)[C@H](C)C(=O)NC(=O)[C@H]([O-])[C@@H](O)[C@H](O)[C@@H](Oc1ccccc1)C(=O)NC(=O)[C@@H](C)C(C)C |
Structure |
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