Reaction Details |
| Report a problem with these data |
Target | Gag-Pol polyprotein [489-587] |
---|
Ligand | BDBM346 |
---|
Substrate/Competitor | n/a |
---|
Meas. Tech. | ChEMBL_302776 (CHEMBL838839) |
---|
Ki | 3.1±n/a nM |
---|
Citation | Shuman, CF; Vrang, L; Danielson, UH Improved structure-activity relationship analysis of HIV-1 protease inhibitors using interaction kinetic data. J Med Chem47:5953-61 (2004) [PubMed] Article |
---|
More Info.: | Get all data from this article, Assay Method |
---|
|
Gag-Pol polyprotein [489-587] |
---|
Name: | Gag-Pol polyprotein [489-587] |
Synonyms: | Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol |
Type: | Enzyme Subunit |
Mol. Mass.: | 10781.16 |
Organism: | Human immunodeficiency virus type 1 |
Description: | P04585[489-587] |
Residue: | 99 |
Sequence: | PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
|
|
|
BDBM346 |
---|
n/a |
---|
Name | BDBM346 |
Synonyms: | (3R,4S,5S,6R)-4,5-dihydroxy-2,7-bis({[4-(hydroxymethyl)phenyl]methyl})-3,6-bis(phenoxymethyl)-1,2,7-thiadiazepane-1,1-dione | CHEMBL340616 | Cyclic Sulfamide deriv. 24 |
Type | Small organic molecule |
Emp. Form. | C34H38N2O8S |
Mol. Mass. | 634.739 |
SMILES | OCc1ccc(CN2[C@H](COc3ccccc3)[C@H](O)[C@@H](O)[C@@H](COc3ccccc3)N(Cc3ccc(CO)cc3)S2(=O)=O)cc1 |r| |
Structure |
|