| Reaction Details |
|---|
 | Report a problem with these data |
| Target | C-8 sterol isomerase ERG2 |
|---|
| Ligand | BDBM50080017 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_303390 (CHEMBL839961) |
|---|
| Ki | 1±n/a nM |
|---|
| Citation |  Laggner, C; Schieferer, C; Fiechtner, B; Poles, G; Hoffmann, RD; Glossmann, H; Langer, T; Moebius, FF Discovery of high-affinity ligands of sigma1 receptor, ERG2, and emopamil binding protein by pharmacophore modeling and virtual screening. J Med Chem48:4754-64 (2005) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| C-8 sterol isomerase ERG2 |
|---|
| Name: | C-8 sterol isomerase ERG2 |
|---|
| Synonyms: | C-8 sterol isomerase | Delta-8--delta-7 sterol isomerase | ERG2 | ERG2_YEAST |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 24892.29 |
|---|
| Organism: | Saccharomyces cerevisiae |
|---|
| Description: | ChEMBL_303390 |
|---|
| Residue: | 222 |
|---|
| Sequence: | MKFFPLLLLIGVVGYIMNVLFTTWLPTNYMFDPKTLNEICNSVISKHNAAEGLSTEDLLQ
DVRDALASHYGDEYINRYVKEEWVFNNAGGAMGQMIILHASVSEYLILFGTAVGTEGHTG
VHFADDYFTILHGTQIAALPYATEAEVYTPGMTHHLKKGYAKQYSMPGGSFALELAQGWI
PCMLPFGFLDTFSSTLDLYTLYRTVYLTARDMGKNLLQNKKF
|
|
|
|---|
| BDBM50080017 |
|---|
| n/a |
|---|
| Name | BDBM50080017 |
|---|
| Synonyms: | (+/-)-[2-(4-benzylpiperidino)-1-(4-hydroxyphenyl)-1-propanol] | (+/-)-ifenprodil | -(2-(4-benzylpiperidin-1-yl)-1-hydroxypropyl)phenol | 4-((1S,2R)-2-(4-benzylpiperidin-1-yl)-1-hydroxypropyl)phenol | 4-(2-(4-benzylpiperidin-1-yl)-1-hydroxypropyl)phenol | 4-[(1S,2R)-2-(4-Benzyl-piperidin-1-yl)-1-hydroxy-propyl]-phenol | 4-[2-(4-Benzyl-piperidin-1-yl)-1-hydroxy-propyl]-phenol | CHEMBL113830 | ifenprodil |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C21H27NO2 |
|---|
| Mol. Mass. | 325.4446 |
|---|
| SMILES | C[C@H]([C@@H](O)c1ccc(O)cc1)N1CCC(Cc2ccccc2)CC1 |r| |
|---|
| Structure | 
|
|---|
Search and Browse
