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TargetAdenosine receptor A1
LigandBDBM50171366
Substrate/Competitorn/a
Meas. Tech.ChEMBL_304269 (CHEMBL829870)
EC50 8300±n/a nM
Citation Chordia, MD; Zigler, M; Murphree, LJ; Figler, H; Macdonald, TL; Olsson, RA; Linden, J 6-aryl-8H-indeno[1,2-d]thiazol-2-ylamines: A1 adenosine receptor agonist allosteric enhancers having improved potency. J Med Chem48:5131-9 (2005) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Adenosine receptor A1
Name:Adenosine receptor A1
Synonyms:A1 adenosine receptor (hA1) | A1AR | AA1R_HUMAN | ADENOSINE A1 | ADORA1 | Adenosine A1 receptor (A1AR) | Adenosine A1-receptor | Adenosine receptor A1 (A1) | Adenosine receptor A1 (hA1) | Adenosine transporter (AdT)
Type:G Protein-Coupled Receptor (GPCR)
Mol. Mass.:36520.92
Organism:Homo sapiens (Human)
Description:P30542
Residue:326
Sequence:
MPPSISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGA
LVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKMVVT
PRRAAVAIAGCWILSFVVGLTPMFGWNNLSAVERAWAANGSMGEPVIKCEFEKVISMEYM
VYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALIL
FLFALSWLPLHILNCITLFCPSCHKPSILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFL
KIWNDHFRCQPAPPIDEDLPEERPDD
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  Blast E-value cutoff:
BDBM50171366
n/a
NameBDBM50171366
Synonyms:6-(2-Nitro-phenyl)-8H-indeno[1,2-d]thiazol-2-yl-ammonium; iodide | CHEMBL193158 | ChEMBL_318083
TypeSmall organic molecule
Emp. Form.C16H12N3O2S
Mol. Mass.310.35
SMILES[NH3+]c1nc-2c(Cc3cc(ccc-23)-c2ccccc2[N+]([O-])=O)s1
Structure
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