| Reaction Details |
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 | Report a problem with these data |
| Target | Glycogen phosphorylase, muscle form |
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| Ligand | BDBM50172983 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_321381 (CHEMBL881759) |
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| IC50 | 140±n/a nM |
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| Citation |  Dudash, J; Zhang, Y; Moore, JB; Look, R; Liang, Y; Beavers, MP; Conway, BR; Rybczynski, PJ; Demarest, KT Synthesis and evaluation of 3-anilino-quinoxalinones as glycogen phosphorylase inhibitors. Bioorg Med Chem Lett15:4790-3 (2005) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Glycogen phosphorylase, muscle form |
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| Name: | Glycogen phosphorylase, muscle form |
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| Synonyms: | Glycogen phosphorylase, muscle form | Muscle glycogen phosphorylase | Myophosphorylase | PYGM | PYGM_HUMAN |
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| Type: | PROTEIN |
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| Mol. Mass.: | 97097.45 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1449751 |
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| Residue: | 842 |
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| Sequence: | MSRPLSDQEKRKQISVRGLAGVENVTELKKNFNRHLHFTLVKDRNVATPRDYYFALAHTV
RDHLVGRWIRTQQHYYEKDPKRIYYLSLEFYMGRTLQNTMVNLALENACDEATYQLGLDM
EELEEIEEDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEFGIFNQKISGGWQMEEA
DDWLRYGNPWEKARPEFTLPVHFYGHVEHTSQGAKWVDTQVVLAMPYDTPVPGYRNNVVN
TMRLWSAKAPNDFNLKDFNVGGYIQAVLDRNLAENISRVLYPNDNFFEGKELRLKQEYFV
VAATLQDIIRRFKSSKFGCRDPVRTNFDAFPDKVAIQLNDTHPSLAIPELMRILVDLERM
DWDKAWDVTVRTCAYTNHTVLPEALERWPVHLLETLLPRHLQIIYEINQRFLNRVAAAFP
GDVDRLRRMSLVEEGAVKRINMAHLCIAGSHAVNGVARIHSEILKKTIFKDFYELEPHKF
QNKTNGITPRRWLVLCNPGLAEVIAERIGEDFISDLDQLRKLLSFVDDEAFIRDVAKVKQ
ENKLKFAAYLEREYKVHINPNSLFDIQVKRIHEYKRQLLNCLHVITLYNRIKREPNKFFV
PRTVMIGGKAAPGYHMAKMIIRLVTAIGDVVNHDPAVGDRLRVIFLENYRVSLAEKVIPA
ADLSEQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGEENFFIFGMRVEDVD
KLDQRGYNAQEYYDRIPELRQVIEQLSSGFFSPKQPDLFKDIVNMLMHHDRFKVFADYED
YIKCQEKVSALYKNPREWTRMVIRNIATSGKFSSDRTIAQYAREIWGVEPSRQRLPAPDE
AI
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| BDBM50172983 |
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| n/a |
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| Name | BDBM50172983 |
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| Synonyms: | 4-(7-Fluoro-4-methyl-3-oxo-3,4-dihydro-quinoxalin-2-ylamino)-N-thiophen-2-ylmethyl-benzamide | CHEMBL193734 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H17FN4O2S |
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| Mol. Mass. | 408.449 |
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| SMILES | Cn1c2ccc(F)cc2nc(Nc2ccc(cc2)C(=O)NCc2cccs2)c1=O |
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| Structure | 
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