| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Protein-S-isoprenylcysteine O-methyltransferase |
|---|
| Ligand | BDBM50174223 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_321447 (CHEMBL880255) |
|---|
| IC50 | 2400±n/a nM |
|---|
| Citation |  Henriksen, BS; Anderson, JL; Hrycyna, CA; Gibbs, RA Synthesis of desthio prenylcysteine analogs: sulfur is important for biological activity. Bioorg Med Chem Lett15:5080-3 (2005) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Protein-S-isoprenylcysteine O-methyltransferase |
|---|
| Name: | Protein-S-isoprenylcysteine O-methyltransferase |
|---|
| Synonyms: | Isoprenylcysteine carboxyl methyltransferase | STE14 | STE14_YEAST |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 27893.87 |
|---|
| Organism: | Saccharomyces cerevisiae |
|---|
| Description: | ChEMBL_321482 |
|---|
| Residue: | 239 |
|---|
| Sequence: | MHQDFQEDEHEYPDIRRNPLHEVTMTSYILGILLGIFVGLFPQIRFKNFNLFIIALSLFH
FLEYYITAKYNPLKVHSESFLLNNGKSYMAAHSFAILECLVESFLFPDLKIFSYSLATKL
CTVLGCLLVILGQYTRTIAMHTAGHSFSHIVKTKKESDHVLVKTGVYSWSRHPSYLGFFW
WAIGTQLLLLNPLSLVIFIFVLWKFFSDRIRVEEKYLIEFFSAEYIEYKNKVGVGIPFI
|
|
|
|---|
| BDBM50174223 |
|---|
| n/a |
|---|
| Name | BDBM50174223 |
|---|
| Synonyms: | 2-(3-Octyl-6-phenyl-indol-1-yl)-acetamide | CHEMBL198274 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C24H30N2O |
|---|
| Mol. Mass. | 362.5078 |
|---|
| SMILES | CCCCCCCCc1cn(CC(N)=O)c2cc(ccc12)-c1ccccc1 |
|---|
| Structure | 
|
|---|
Search and Browse
