| Reaction Details |
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 | Report a problem with these data |
| Target | Aryl hydrocarbon receptor |
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| Ligand | BDBM50191422 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_365417 (CHEMBL867900) |
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| IC50 | 24000±n/a nM |
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| Citation |  Ferandin, Y; Bettayeb, K; Kritsanida, M; Lozach, O; Polychronopoulos, P; Magiatis, P; Skaltsounis, AL; Meijer, L 3'-Substituted 7-halogenoindirubins, a new class of cell death inducing agents. J Med Chem49:4638-49 (2006) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Aryl hydrocarbon receptor |
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| Name: | Aryl hydrocarbon receptor |
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| Synonyms: | AHR | AHR_HUMAN | BHLHE76 | Class E basic helix-loop-helix protein 76 | aryl hydrocarbon receptor precursor |
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| Type: | PROTEIN |
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| Mol. Mass.: | 96143.77 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1503828 |
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| Residue: | 848 |
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| Sequence: | MNSSSANITYASRKRRKPVQKTVKPIPAEGIKSNPSKRHRDRLNTELDRLASLLPFPQDV
INKLDKLSVLRLSVSYLRAKSFFDVALKSSPTERNGGQDNCRAANFREGLNLQEGEFLLQ
ALNGFVLVVTTDALVFYASSTIQDYLGFQQSDVIHQSVYELIHTEDRAEFQRQLHWALNP
SQCTESGQGIEEATGLPQTVVCYNPDQIPPENSPLMERCFICRLRCLLDNSSGFLAMNFQ
GKLKYLHGQKKKGKDGSILPPQLALFAIATPLQPPSILEIRTKNFIFRTKHKLDFTPIGC
DAKGRIVLGYTEAELCTRGSGYQFIHAADMLYCAESHIRMIKTGESGMIVFRLLTKNNRW
TWVQSNARLLYKNGRPDYIIVTQRPLTDEEGTEHLRKRNTKLPFMFTTGEAVLYEATNPF
PAIMDPLPLRTKNGTSGKDSATTSTLSKDSLNPSSLLAAMMQQDESIYLYPASSTSSTAP
FENNFFNESMNECRNWQDNTAPMGNDTILKHEQIDQPQDVNSFAGGHPGLFQDSKNSDLY
SIMKNLGIDFEDIRHMQNEKFFRNDFSGEVDFRDIDLTDEILTYVQDSLSKSPFIPSDYQ
QQQSLALNSSCMVQEHLHLEQQQQHHQKQVVVEPQQQLCQKMKHMQVNGMFENWNSNQFV
PFNCPQQDPQQYNVFTDLHGISQEFPYKSEMDSMPYTQNFISCNQPVLPQHSKCTELDYP
MGSFEPSPYPTTSSLEDFVTCLQLPENQKHGLNPQSAIITPQTCYAGAVSMYQCQPEPQH
THVGQMQYNPVLPGQQAFLNKFQNGVLNETYPAELNNINNTQTTTHLQPLHHPSEARPFP
DLTSSGFL
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| BDBM50191422 |
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| n/a |
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| Name | BDBM50191422 |
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| Synonyms: | (2'Z,3'E)-1-methyl-7-bromoindirubin-3'-[O-(2-dimethylaminoethyl)oxime] hydrochloride | CHEMBL213077 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H22BrN4O2 |
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| Mol. Mass. | 442.328 |
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| SMILES | C[NH+](C)CCO\N=C1\C(=Nc2ccccc12)c1c(O)n(C)c2c(Br)cccc12 |c:8| |
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| Structure | 
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