| Reaction Details |
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 | Report a problem with these data |
| Target | Kappa-type opioid receptor |
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| Ligand | BDBM50190364 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_376243 (CHEMBL869298) |
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| Ki | >10000±n/a nM |
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| Citation |  Zhang, Q; Keenan, SM; Peng, Y; Nair, AC; Yu, SJ; Howells, RD; Welsh, WJ Discovery of novel triazole-based opioid receptor antagonists. J Med Chem49:4044-7 (2006) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Kappa-type opioid receptor |
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| Name: | Kappa-type opioid receptor |
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| Synonyms: | K-OR-1 | KOR-1 | Kappa-opioid receptor (KOR) | Kappa-type opioid receptor (KOPR) | Kappa-type opioid receptor (KOR) | Kappa-type opioid receptor (Kappa) | OPIATE Kappa | OPRK | OPRK1 | OPRK_HUMAN | kappa opioid receptor (KOR) |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 42648.76 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P41145 |
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| Residue: | 380 |
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| Sequence: | MDSPIQIFRGEPGPTCAPSACLPPNSSAWFPGWAEPDSNGSAGSEDAQLEPAHISPAIPV
IITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSTVYL
MNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINI
CIWLLSSSVGISAIVLGGTKVREDVDVIECSLQFPDDDYSWWDLFMKICVFIFAFVIPVL
IIIVCYTLMILRLKSVRLLSGSREKDRNLRRITRLVLVVVAVFVVCWTPIHIFILVEALG
STSHSTAALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFPLKMRMERQSTSRV
RNTVQDPAYLRDIDGMNKPV
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| BDBM50190364 |
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| n/a |
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| Name | BDBM50190364 |
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| Synonyms: | 1-{3-[3-(tert-butyl) phenyl]-(1,2,4-triazol-4-yl) }-3-methoxybenzene | CHEMBL212510 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H21N3O |
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| Mol. Mass. | 307.3895 |
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| SMILES | COc1cccc(c1)-n1cnnc1-c1ccc(cc1)C(C)(C)C |
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| Structure | 
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