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Target2-dehydropantoate 2-reductase
LigandBDBM50192451
Substrate/Competitorn/a
Meas. Tech.ChEMBL_382751 (CHEMBL854530)
Kd 5800±n/a nM
Citation Ciulli, AWilliams, GSmith, AGBlundell, TLAbell, C Probing hot spots at protein-ligand binding sites: a fragment-based approach using biophysical methods. J Med Chem49:4992-5000 (2006) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
2-dehydropantoate 2-reductase
Name:2-dehydropantoate 2-reductase
Synonyms:Ketopantoate reductase | PANE_ECOLI | apbA | panE
Type:PROTEIN
Mol. Mass.:33866.35
Organism:Escherichia coli (strain K12)
Description:ChEMBL_382751
Residue:303
Sequence:
MKITVLGCGALGQLWLTALCKQGHEVQGWLRVPQPYCSVNLVETDGSIFNESLTANDPDF
LATSDLLLVTLKAWQVSDAVKSLASTLPVTTPILLIHNGMGTIEELQNIQQPLLMGTTTH
AARRDGNVIIHVANGITHIGPARQQDGDYSYLADILQTVLPDVAWHNNIRAELWRKLAVN
CVINPLTAIWNCPNGELRHHPQEIMQICEEVAAVIEREGHHTSAEDLRDYVMQVIDATAE
NISSMLQDIRALRHTEIDYINGFLLRRARAHGIAVPENTRLFEMVKRKESEYERIGTGLP
RPW
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BDBM50192451
n/a
NameBDBM50192451
Synonyms:CHEMBL213053 | NADP+
TypeSmall organic molecule
Emp. Form.C21H25N7O17P3
Mol. Mass.740.3828
SMILESNC(=O)c1ccc[n+](c1)C1OC(COP([O-])(=O)OP([O-])(=O)OC[C@H]2O[C@H]([C@H](OP([O-])([O-])=O)[C@@H]2O)n2cnc3c(N)ncnc23)[C@H](O)[C@@H]1O
Structure
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