| Reaction Details |
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 | Report a problem with these data |
| Target | Alpha-1B adrenergic receptor |
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| Ligand | BDBM50187757 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_384613 (CHEMBL866127) |
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| Ki | 7.7±n/a nM |
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| Citation |  Hayashi, R; Ohmori, E; Isogaya, M; Moriwaki, M; Kumagai, H Design and synthesis of selective alpha1B adrenoceptor antagonists. Bioorg Med Chem Lett16:4045-7 (2006) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Alpha-1B adrenergic receptor |
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| Name: | Alpha-1B adrenergic receptor |
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| Synonyms: | ADA1B_RAT | Adra1b | Alpha 1B-adrenoceptor | Alpha 1B-adrenoreceptor | Alpha adrenergic receptor 1A and 1B | Alpha-1 Adrenergic Receptor | Alpha-1Adrenoceptor | Alpha-1B adrenergic receptor | Alpha-1B adrenoreceptor | adrenergic Alpha1B |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 56606.71 |
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| Organism: | Rattus norvegicus (rat) |
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| Description: | Receptor binding assays were performed using rat cortical membranes. |
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| Residue: | 515 |
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| Sequence: | MNPDLDTGHNTSAPAHWGELKDDNFTGPNQTSSNSTLPQLDVTRAISVGLVLGAFILFAI
VGNILVILSVACNRHLRTPTNYFIVNLAIADLLLSFTVLPFSATLEVLGYWVLGRIFCDI
WAAVDVLCCTASILSLCAISIDRYIGVRYSLQYPTLVTRRKAILALLSVWVLSTVISIGP
LLGWKEPAPNDDKECGVTEEPFYALFSSLGSFYIPLAVILVMYCRVYIVAKRTTKNLEAG
VMKEMSNSKELTLRIHSKNFHEDTLSSTKAKGHNPRSSIAVKLFKFSREKKAAKTLGIVV
GMFILCWLPFFIALPLGSLFSTLKPPDAVFKVVFWLGYFNSCLNPIIYPCSSKEFKRAFM
RILGCQCRGGRRRRRRRRLGACAYTYRPWTRGGSLERSQSRKDSLDDSGSCMSGTQRTLP
SASPSPGYLGRGTQPPVELCAFPEWKPGALLSLPEPPGRRGRLDSGPLFTFKLLGDPESP
GTEGDTSNGGCDTTTDLANGQPGFKSNMPLAPGHF
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| BDBM50187757 |
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| n/a |
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| Name | BDBM50187757 |
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| Synonyms: | 1-(3-(4-(benzofuran-3-yl)piperidin-1-yl)propyl)piperidine dihydrochloride | CHEMBL534944 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H30N2O |
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| Mol. Mass. | 326.4757 |
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| SMILES | C(CN1CCCCC1)CN1CCC(CC1)c1coc2ccccc12 |
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| Structure | 
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