| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Oxytocin receptor |
|---|
| Ligand | BDBM50205309 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_425927 (CHEMBL907382) |
|---|
| Ki | 64±n/a nM |
|---|
| Citation |  Pena, A; Murat, B; Trueba, M; Ventura, MA; Wo, NC; Szeto, HH; Cheng, LL; Stoev, S; Guillon, G; Manning, M Design and synthesis of the first selective agonists for the rat vasopressin V(1b) receptor: based on modifications of deamino-[Cys1]arginine vasopressin at positions 4 and 8. J Med Chem50:835-47 (2007) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Oxytocin receptor |
|---|
| Name: | Oxytocin receptor |
|---|
| Synonyms: | OT-R | OXYR_RAT | Otr | Oxtr | Oxytocin |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 42889.28 |
|---|
| Organism: | RAT |
|---|
| Description: | Oxytocin OXTR RAT::P70536 |
|---|
| Residue: | 388 |
|---|
| Sequence: | MEGTPAANWSVELDLGSGVPPGEEGNRTAGPPQRNEALARVEVAVLCLILFLALSGNACV
LLALRTTRHKHSRLFFFMKHLSIADLVVAVFQVLPQLLWDITFRFYGPDLLCRLVKYLQV
VGMFASTYLLLLMSLDRCLAICQPLRSLRRRTDRLAVLGTWLGCLVASAPQVHIFSLREV
ADGVFDCWAVFIQPWGPKAYVTWITLAVYIVPVIVLAACYGLISFKIWQNLRLKTAAAAA
AAEGNDAAGGAGRAALARVSSVKLISKAKIRTVKMTFIIVLAFIVCWTPFFFVQMWSVWD
VNAPKEASAFIIAMLLASLNSCCNPWIYMLFTGHLFHELVQRFFCCSARYLKGSRPGETS
VSKKSNSSTFVLSRRSSSQRSCSQPSSA
|
|
|
|---|
| BDBM50205309 |
|---|
| n/a |
|---|
| Name | BDBM50205309 |
|---|
| Synonyms: | CHEMBL412972 | d[Leu4,Lys8]VP |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C47H67N11O11S2 |
|---|
| Mol. Mass. | 1026.232 |
|---|
| SMILES | CC(C)C[C@@H]1NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)CCSSC[C@H](NC(=O)[C@H](CC(N)=O)NC1=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)NCC(N)=O |
|---|
| Structure | 
|
|---|
Search and Browse
