| Reaction Details |
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 | Report a problem with these data |
| Target | Heme oxygenase 2 |
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| Ligand | BDBM84847 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_435912 (CHEMBL905313) |
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| IC50 | >100000±n/a nM |
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| Citation |  Roman, G; Riley, JG; Vlahakis, JZ; Kinobe, RT; Brien, JF; Nakatsu, K; Szarek, WA Heme oxygenase inhibition by 2-oxy-substituted 1-(1H-imidazol-1-yl)-4-phenylbutanes: effect of halogen substitution in the phenyl ring. Bioorg Med Chem15:3225-34 (2007) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Heme oxygenase 2 |
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| Name: | Heme oxygenase 2 |
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| Synonyms: | HMOX2_RAT | Heme Oxygenase 2 (HO-2) | Heme oxygenase 2 | Hmox2 |
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| Type: | Enzyme |
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| Mol. Mass.: | 35754.99 |
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| Organism: | Rattus norvegicus (rat) |
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| Description: | HO-2 obtained from rat brain was used in enzyme assays. |
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| Residue: | 315 |
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| Sequence: | MSSEVETSEGVDESENNSTAPEKENHTKMADLSELLKEGTKEAHDRAENTQFVKDFLKGN
IKKELFKLATTALYFTYSALEEEMDRNKDHPAFAPLYFPTELHRKEALIKDMEYFFGENW
EEQVKCSEAAQKYVDRIHYVGQNEPELLVAHAYTRYMGDLSGGQVLKKVAQRALKLPSTG
EGTQFYLFEHVDNAQQFKQFYRARMNALDLSMKTKERIVEEANKAFEYNMQIFSELDQAG
SMLTKETLEDGLPVHDGKGDVRKCPFYAAQPDKGTLGGSNCPFRTAMAVLRKPSLQLILA
ASVALVAGLLAWYYM
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| BDBM84847 |
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| n/a |
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| Name | BDBM84847 |
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| Synonyms: | 1-azolyl-4-phenyl-2-butanone, 49a | CHEMBL558183 |
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| Type | n/a |
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| Emp. Form. | C15H18N2O2 |
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| Mol. Mass. | 258.3156 |
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| SMILES | C(CC1(Cn2ccnc2)OCCO1)c1ccccc1 |
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| Structure | 
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