| Reaction Details |
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 | Report a problem with these data |
| Target | Heme oxygenase 2 |
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| Ligand | BDBM50207199 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_435912 (CHEMBL905313) |
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| IC50 | >100000±n/a nM |
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| Citation |  Roman, G; Riley, JG; Vlahakis, JZ; Kinobe, RT; Brien, JF; Nakatsu, K; Szarek, WA Heme oxygenase inhibition by 2-oxy-substituted 1-(1H-imidazol-1-yl)-4-phenylbutanes: effect of halogen substitution in the phenyl ring. Bioorg Med Chem15:3225-34 (2007) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Heme oxygenase 2 |
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| Name: | Heme oxygenase 2 |
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| Synonyms: | HMOX2_RAT | Heme Oxygenase 2 (HO-2) | Heme oxygenase 2 | Hmox2 |
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| Type: | Enzyme |
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| Mol. Mass.: | 35754.99 |
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| Organism: | Rattus norvegicus (rat) |
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| Description: | HO-2 obtained from rat brain was used in enzyme assays. |
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| Residue: | 315 |
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| Sequence: | MSSEVETSEGVDESENNSTAPEKENHTKMADLSELLKEGTKEAHDRAENTQFVKDFLKGN
IKKELFKLATTALYFTYSALEEEMDRNKDHPAFAPLYFPTELHRKEALIKDMEYFFGENW
EEQVKCSEAAQKYVDRIHYVGQNEPELLVAHAYTRYMGDLSGGQVLKKVAQRALKLPSTG
EGTQFYLFEHVDNAQQFKQFYRARMNALDLSMKTKERIVEEANKAFEYNMQIFSELDQAG
SMLTKETLEDGLPVHDGKGDVRKCPFYAAQPDKGTLGGSNCPFRTAMAVLRKPSLQLILA
ASVALVAGLLAWYYM
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| BDBM50207199 |
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| n/a |
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| Name | BDBM50207199 |
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| Synonyms: | 1-((2-(2-(4-bromophenyl)ethyl)-1,3-dioxolan-2-yl)methyl)-1H-imidazole hydrochloride | CHEMBL539857 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H17BrN2O2 |
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| Mol. Mass. | 337.212 |
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| SMILES | Brc1ccc(CCC2(Cn3ccnc3)OCCO2)cc1 |
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| Structure | 
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