| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Enoyl-acyl-carrier protein reductase |
|---|
| Ligand | BDBM8425 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_436469 (CHEMBL904776) |
|---|
| Ki | 510±n/a nM |
|---|
| Citation |  Kumar, G; Parasuraman, P; Sharma, SK; Banerjee, T; Karmodiya, K; Surolia, N; Surolia, A Discovery of a rhodanine class of compounds as inhibitors of Plasmodium falciparum enoyl-acyl carrier protein reductase. J Med Chem50:2665-75 (2007) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Enoyl-acyl-carrier protein reductase |
|---|
| Name: | Enoyl-acyl-carrier protein reductase |
|---|
| Synonyms: | n/a |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 49770.86 |
|---|
| Organism: | Plasmodium falciparum |
|---|
| Description: | ChEMBL_795989 |
|---|
| Residue: | 432 |
|---|
| Sequence: | MNKISQRLLFLFLHFYTTVCFIQNNTQKTFHNVLQNEQIRGKEKAFYRKEKRENIFIGNK
MKHVHNMNNTHNNNHYMEKEEQDASNINKIKEENKNEDICFIAGIGDTNGYGWGIAKELS
KRNVKIIFGIWPPVYNIFMKNYKNGKFDNDMIIDKDKKMNILDMLPFDASFDTANDIDEE
TKNNKRYNMLQNYPIEDVANLIHQKYGKINMLVHSLANAKEVQKDLLNTSRKGYLDALSK
SSYSLISLCKYFVNIMKPQSSIISLTYHASQKVVPGYGGGMSSAKAALESDTRVLAYHLG
RNYNIRINTISAGPLKSRAATAINKLNNTYENNTNQNKNRNSHDVHNIMNNSGEKEEKKN
SASQNYTFIDYAIEYSEKYAPLRQKLLSTDIGSVASFLLSRESRAITGQTIYVDNGLNIM
FLPDDIYRNENE
|
|
|
|---|
| BDBM8425 |
|---|
| n/a |
|---|
| Name | BDBM8425 |
|---|
| Synonyms: | (5Z)-5-{[5-(3,4-dichlorophenyl)furan-2-yl]methylidene}-2-sulfanylidene-1,3-thiazolidin-4-one | CHEMBL227618 | Rhodanine-furan analogue 12 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C14H7Cl2NO2S2 |
|---|
| Mol. Mass. | 356.247 |
|---|
| SMILES | Clc1ccc(cc1Cl)-c1ccc(\C=C2/SC(=S)NC2=O)o1 |
|---|
| Structure | 
|
|---|
Search and Browse
