| Reaction Details |
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 | Report a problem with these data |
| Target | Bcl-2-like protein 2 |
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| Ligand | BDBM50202275 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_441639 (CHEMBL891870) |
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| Ki | 24100±n/a nM |
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| Citation |  Xing, C; Wang, L; Tang, X; Sham, YY Development of selective inhibitors for anti-apoptotic Bcl-2 proteins from BHI-1. Bioorg Med Chem15:2167-76 (2007) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Bcl-2-like protein 2 |
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| Name: | Bcl-2-like protein 2 |
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| Synonyms: | Apoptosis regulator Bcl-W | B2CL2_HUMAN | BCL-W | BCL2L2 | BCLW | Bcl-2-like protein 2 | Bcl2-L-2 | KIAA0271 |
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| Type: | Protein |
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| Mol. Mass.: | 20742.61 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 193 |
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| Sequence: | MATPASAPDTRALVADFVGYKLRQKGYVCGAGPGEGPAADPLHQAMRAAGDEFETRFRRT
FSDLAAQLHVTPGSAQQRFTQVSDELFQGGPNWGRLVAFFVFGAALCAESVNKEMEPLVG
QVQEWMVAYLETQLADWIHSSGGWAEFTALYGDGALEEARRLREGNWASVRTVLTGAVAL
GALVTVGAFFASK
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|
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| BDBM50202275 |
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| n/a |
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| Name | BDBM50202275 |
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| Synonyms: | 2-[5-(1-phenylbutylidene)-4-oxo-2-thioxothiazolidin-3-yl]-4-methylpentanoic acid | CHEMBL242126 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H23NO3S2 |
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| Mol. Mass. | 377.521 |
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| SMILES | CCC\C(=C1\SC(=S)N([C@@H](CC(C)C)C(O)=O)C1=O)c1ccccc1 |
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| Structure | 
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