| Reaction Details |
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 | Report a problem with these data |
| Target | Beta-2 adrenergic receptor |
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| Ligand | BDBM50221773 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_446229 (CHEMBL895334) |
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| EC50 | 16000±n/a nM |
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| Citation |  Buonsanti, MF; Bertinaria, M; Stilo, AD; Cena, C; Fruttero, R; Gasco, A Nitric oxide donor beta2-agonists: furoxan derivatives containing the fenoterol moiety and related furazans. J Med Chem50:5003-11 (2007) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Beta-2 adrenergic receptor |
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| Name: | Beta-2 adrenergic receptor |
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| Synonyms: | ADRB2_RAT | Adrb2 | Adrb2r | Adrenergic receptor beta |
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| Type: | PROTEIN |
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| Mol. Mass.: | 46896.26 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_38603 |
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| Residue: | 418 |
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| Sequence: | MEPHGNDSDFLLAPNGSRAPGHDITQERDEAWVVGMAILMSVIVLAIVFGNVLVITAIAK
FERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWNFGNFWCEFWTSIDVLCVTAS
IETLCVIAVDRYVAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHKQ
AIDCYAKETCCDFFTNQAYAIASSIVSFYVPLVVMVFVYSRVFQVAKRQLQKIDKSEGRF
HAQNLSQVEQDGRSGHGLRSSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIRA
NLIPKEVYILLNWLGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSSKTYGNGYSSNSNG
RTDYTGEQSAYQLGQEKENELLCEEAPGMEGFVNCQGTVPSLSIDSQGRNCNTNDSPL
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| BDBM50221773 |
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| n/a |
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| Name | BDBM50221773 |
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| Synonyms: | 4-(4-{2-[2-(3,5-dihydroxy-phenyl)-2-hydroxy-ethylamino]-propyl}-phenoxymethyl)-2-oxy-furazan-3-carboxylic acid amide | CHEMBL243266 | rac-4-(4-{(2R)-[2-(3,5-dihydroxyphenyl)-(2S)-hydroxyethylamino]propyl}phenoxymethyl)furoxan-3-carboxamide |
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| Type | Small organic molecule |
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| Emp. Form. | C21H24N4O7 |
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| Mol. Mass. | 444.4379 |
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| SMILES | CC(Cc1ccc(OCc2no[n+]([O-])c2C(N)=O)cc1)NCC(O)c1cc(O)cc(O)c1 |w:1.0,22.24| |
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| Structure | 
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