| Reaction Details |
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 | Report a problem with these data |
| Target | Sphingosine 1-phosphate receptor 1 |
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| Ligand | BDBM50197421 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_453246 (CHEMBL902400) |
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| EC50 | >1000±n/a nM |
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| Citation |  Hanessian, S; Charron, G; Billich, A; Guerini, D Constrained azacyclic analogues of the immunomodulatory agent FTY720 as molecular probes for sphingosine 1-phosphate receptors. Bioorg Med Chem Lett17:491-4 (2007) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Sphingosine 1-phosphate receptor 1 |
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| Name: | Sphingosine 1-phosphate receptor 1 |
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| Synonyms: | CHEDG1 | EDG1 | Endothelial differentiation G-protein coupled receptor 1 | S1P receptor | S1P1 | S1PR1 | S1PR1_HUMAN | Sphingosine 1-phosphate receptor 1 (S1PR1) | Sphingosine 1-phosphate receptor Edg-1 |
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| Type: | Enzyme |
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| Mol. Mass.: | 42836.02 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P21453 |
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| Residue: | 382 |
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| Sequence: | MGPTSVPLVKAHRSSVSDYVNYDIIVRHYNYTGKLNISADKENSIKLTSVVFILICCFII
LENIFVLLTIWKTKKFHRPMYYFIGNLALSDLLAGVAYTANLLLSGATTYKLTPAQWFLR
EGSMFVALSASVFSLLAIAIERYITMLKMKLHNGSNNFRLFLLISACWVISLILGGLPIM
GWNCISALSSCSTVLPLYHKHYILFCTTVFTLLLLSIVILYCRIYSLVRTRSRRLTFRKN
ISKASRSSEKSLALLKTVIIVLSVFIACWAPLFILLLLDVGCKVKTCDILFRAEYFLVLA
VLNSGTNPIIYTLTNKEMRRAFIRIMSCCKCPSGDSAGKFKRPIIAGMEFSRSKSDNSSH
PQKDEGDNPETIMSSGNVNSSS
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| BDBM50197421 |
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| n/a |
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| Name | BDBM50197421 |
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| Synonyms: | (2S,3R,5R)-2-[(hydrogen phosphonatooxy)methyl]-5-(hydroxymethyl)-3-(4-octylphenyl)pyrrolidin-1-ium | CHEMBL247698 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H34NO5P |
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| Mol. Mass. | 399.4614 |
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| SMILES | CCCCCCCCc1ccc(cc1)[C@H]1C[C@H](CO)[NH2+][C@@H]1COP(O)([O-])=O |w:23.26| |
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| Structure | 
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