| Reaction Details |
|---|
 | Report a problem with these data |
| Target | P2Y purinoceptor 2 |
|---|
| Ligand | BDBM50195825 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_453274 (CHEMBL902429) |
|---|
| EC50 | 5±n/a nM |
|---|
| Citation |  Davenport, RJ; Diaz, P; Galvin, FC; Lloyd, S; Mack, SR; Owens, R; Sabin, V; Wynn, J Novel nucleotide triphosphates as potent P2Y2 agonists with enhanced stability over UTP. Bioorg Med Chem Lett17:558-61 (2007) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| P2Y purinoceptor 2 |
|---|
| Name: | P2Y purinoceptor 2 |
|---|
| Synonyms: | ATP receptor | P2RU1 | P2RY2 | P2RY2_HUMAN | P2U purinoceptor 1 | P2U1 | P2Y purinoceptor 2 | P2Y2 | Purinergic receptor | Purinergic receptor P2Y2 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 42299.21 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_1455361 |
|---|
| Residue: | 377 |
|---|
| Sequence: | MAADLGPWNDTINGTWDGDELGYRCRFNEDFKYVLLPVSYGVVCVPGLCLNAVALYIFLC
RLKTWNASTTYMFHLAVSDALYAASLPLLVYYYARGDHWPFSTVLCKLVRFLFYTNLYCS
ILFLTCISVHRCLGVLRPLRSLRWGRARYARRVAGAVWVLVLACQAPVLYFVTTSARGGR
VTCHDTSAPELFSRFVAYSSVMLGLLFAVPFAVILVCYVLMARRLLKPAYGTSGGLPRAK
RKSVRTIAVVLAVFALCFLPFHVTRTLYYSFRSLDLSCHTLNAINMAYKVTRPLASANSC
LDPVLYFLAGQRLVRFARDAKPPTGPSPATPARRRLGLRRSDRTDMQRIEDVLGSSEDSR
RTESTPAGSENTKDIRL
|
|
|
|---|
| BDBM50195825 |
|---|
| n/a |
|---|
| Name | BDBM50195825 |
|---|
| Synonyms: | ({[({[(2R,3S,4R,5R)-5-(7-fluoro-1-oxo-1,2-dihydroisoquinolin-2-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)phosphonic acid | CHEMBL399017 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C14H17FNO14P3 |
|---|
| Mol. Mass. | 535.2028 |
|---|
| SMILES | O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP(O)(=O)OP(O)(=O)OP(O)(O)=O)n1ccc2ccc(F)cc2c1=O |w:9.10,13.14| |
|---|
| Structure | 
|
|---|
Search and Browse
