| Reaction Details |
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 | Report a problem with these data |
| Target | P2Y purinoceptor 2 |
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| Ligand | BDBM50197696 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_453274 (CHEMBL902429) |
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| EC50 | 10±n/a nM |
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| Citation |  Davenport, RJ; Diaz, P; Galvin, FC; Lloyd, S; Mack, SR; Owens, R; Sabin, V; Wynn, J Novel nucleotide triphosphates as potent P2Y2 agonists with enhanced stability over UTP. Bioorg Med Chem Lett17:558-61 (2007) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| P2Y purinoceptor 2 |
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| Name: | P2Y purinoceptor 2 |
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| Synonyms: | ATP receptor | P2RU1 | P2RY2 | P2RY2_HUMAN | P2U purinoceptor 1 | P2U1 | P2Y purinoceptor 2 | P2Y2 | Purinergic receptor | Purinergic receptor P2Y2 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 42299.21 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1455361 |
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| Residue: | 377 |
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| Sequence: | MAADLGPWNDTINGTWDGDELGYRCRFNEDFKYVLLPVSYGVVCVPGLCLNAVALYIFLC
RLKTWNASTTYMFHLAVSDALYAASLPLLVYYYARGDHWPFSTVLCKLVRFLFYTNLYCS
ILFLTCISVHRCLGVLRPLRSLRWGRARYARRVAGAVWVLVLACQAPVLYFVTTSARGGR
VTCHDTSAPELFSRFVAYSSVMLGLLFAVPFAVILVCYVLMARRLLKPAYGTSGGLPRAK
RKSVRTIAVVLAVFALCFLPFHVTRTLYYSFRSLDLSCHTLNAINMAYKVTRPLASANSC
LDPVLYFLAGQRLVRFARDAKPPTGPSPATPARRRLGLRRSDRTDMQRIEDVLGSSEDSR
RTESTPAGSENTKDIRL
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| BDBM50197696 |
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| n/a |
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| Name | BDBM50197696 |
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| Synonyms: | ({[({[(2R,3S,4R,5R)-3,4-dihydroxy-5-[5-(trifluoromethyl)-1,3-benzothiazol-2-yl]oxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)phosphonic acid | CHEMBL391317 |
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| Type | Small organic molecule |
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| Emp. Form. | C13H15F3NO13P3S |
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| Mol. Mass. | 575.239 |
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| SMILES | O[C@@H]1[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O[C@H]([C@@H]1O)c1nc2cc(ccc2s1)C(F)(F)F |w:9.9,5.5| |
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| Structure | 
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