| Reaction Details |
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 | Report a problem with these data |
| Target | ATP-citrate synthase |
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| Ligand | BDBM50066683 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_459068 (CHEMBL925175) |
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| Ki | 1000±n/a nM |
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| Citation |  Jain, KS; Kathiravan, MK; Somani, RS; Shishoo, CJ The biology and chemistry of hyperlipidemia. Bioorg Med Chem15:4674-99 (2007) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| ATP-citrate synthase |
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| Name: | ATP-citrate synthase |
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| Synonyms: | ACLY | ACLY_HUMAN |
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| Type: | PROTEIN |
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| Mol. Mass.: | 120848.43 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_455196 |
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| Residue: | 1101 |
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| Sequence: | MSAKAISEQTGKELLYKFICTTSAIQNRFKYARVTPDTDWARLLQDHPWLLSQNLVVKPD
QLIKRRGKLGLVGVNLTLDGVKSWLKPRLGQEATVGKATGFLKNFLIEPFVPHSQAEEFY
VCIYATREGDYVLFHHEGGVDVGDVDAKAQKLLVGVDEKLNPEDIKKHLLVHAPEDKKEI
LASFISGLFNFYEDLYFTYLEINPLVVTKDGVYVLDLAAKVDATADYICKVKWGDIEFPP
PFGREAYPEEAYIADLDAKSGASLKLTLLNPKGRIWTMVAGGGASVVYSDTICDLGGVNE
LANYGEYSGAPSEQQTYDYAKTILSLMTREKHPDGKILIIGGSIANFTNVAATFKGIVRA
IRDYQGPLKEHEVTIFVRRGGPNYQEGLRVMGEVGKTTGIPIHVFGTETHMTAIVGMALG
HRPIPNQPPTAAHTANFLLNASGSTSTPAPSRTASFSESRADEVAPAKKAKPAMPQDSVP
SPRSLQGKSTTLFSRHTKAIVWGMQTRAVQGMLDFDYVCSRDEPSVAAMVYPFTGDHKQK
FYWGHKEILIPVFKNMADAMRKHPEVDVLINFASLRSAYDSTMETMNYAQIRTIAIIAEG
IPEALTRKLIKKADQKGVTIIGPATVGGIKPGCFKIGNTGGMLDNILASKLYRPGSVAYV
SRSGGMSNELNNIISRTTDGVYEGVAIGGDRYPGSTFMDHVLRYQDTPGVKMIVVLGEIG
GTEEYKICRGIKEGRLTKPIVCWCIGTCATMFSSEVQFGHAGACANQASETAVAKNQALK
EAGVFVPRSFDELGEIIQSVYEDLVANGVIVPAQEVPPPTVPMDYSWARELGLIRKPASF
MTSICDERGQELIYAGMPITEVFKEEMGIGGVLGLLWFQKRLPKYSCQFIEMCLMVTADH
GPAVSGAHNTIICARAGKDLVSSLTSGLLTIGDRFGGALDAAAKMFSKAFDSGIIPMEFV
NKMKKEGKLIMGIGHRVKSINNPDMRVQILKDYVRQHFPATPLLDYALEVEKITTSKKPN
LILNVDGLIGVAFVDMLRNCGSFTREEADEYIDIGALNGIFVLGRSMGFIGHYLDQKRLK
QGLYRHPWDDISYVLPEHMSM
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| BDBM50066683 |
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| n/a |
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| Name | BDBM50066683 |
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| Synonyms: | (S)-2-((R)-8-(2,4-dichlorophenyl)-2-hydroxyoctyl)-2-hydroxysuccinic acid | (S)-2-[(R)-8-(2,4-Dichloro-phenyl)-2-hydroxy-octyl]-2-hydroxy-succinic acid | CHEMBL119628 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H24Cl2O6 |
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| Mol. Mass. | 407.286 |
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| SMILES | O[C@H](CCCCCCc1ccc(Cl)cc1Cl)C[C@](O)(CC(O)=O)C(O)=O |
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| Structure | 
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