| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A2b |
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| Ligand | BDBM50224760 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_461292 (CHEMBL927311) |
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| Ki | 8350±n/a nM |
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| Citation |  Cappellacci, L; Franchetti, P; Vita, P; Petrelli, R; Lavecchia, A; Costa, B; Spinetti, F; Martini, C; Klotz, KN; Grifantini, M 5'-Carbamoyl derivatives of 2'-C-methyl-purine nucleosides as selective A1 adenosine receptor agonists: affinity, efficacy, and selectivity for A1 receptor from different species. Bioorg Med Chem16:336-53 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A2b |
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| Name: | Adenosine receptor A2b |
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| Synonyms: | AA2BR_HUMAN | ADENOSINE A2B | ADORA2B | Adenosine receptor A2B (A2B) | Adenosine receptors A2b | Adenosine receptors; A2a & A2b |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 36341.22 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 332 |
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| Sequence: | MLLETQDALYVALELVIAALSVAGNVLVCAAVGTANTLQTPTNYFLVSLAAADVAVGLFA
IPFAITISLGFCTDFYGCLFLACFVLVLTQSSIFSLLAVAVDRYLAICVPLRYKSLVTGT
RARGVIAVLWVLAFGIGLTPFLGWNSKDSATNNCTEPWDGTTNESCCLVKCLFENVVPMS
YMVYFNFFGCVLPPLLIMLVIYIKIFLVACRQLQRTELMDHSRTTLQREIHAAKSLAMIV
GIFALCWLPVHAVNCVTLFQPAQGKNKPKWAMNMAILLSHANSVVNPIVYAYRNRDFRYT
FHKIISRYLLCQADVKSGNGQAGVQPALGVGL
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| BDBM50224760 |
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| n/a |
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| Name | BDBM50224760 |
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| Synonyms: | 2-chloro-N6-cyclopentyl-9H-(2-C-methyl-5-Nmethylcarbamoyl-beta-D-ribofuranosyl)adenine | CHEMBL254064 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H25ClN6O5 |
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| Mol. Mass. | 440.881 |
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| SMILES | CNC(=O)OC[C@H]1O[C@@H](n2cnc3c(NC4CCCC4)nc(Cl)nc23)[C@](C)(O)[C@@H]1O |
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| Structure | 
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