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TargetAmine oxidase [flavin-containing] B
LigandBDBM10989
Substrate/Competitorn/a
Meas. Tech.ChEMBL_462121 (CHEMBL945895)
IC50 4.4±n/a nM
Citation Cavalli, ABolognesi, MLMinarini, ARosini, MTumiatti, VRecanatini, MMelchiorre, C Multi-target-directed ligands to combat neurodegenerative diseases. J Med Chem51:347-72 (2008) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Amine oxidase [flavin-containing] B
Name:Amine oxidase [flavin-containing] B
Synonyms:AOFB_HUMAN | MAO-B | MAOB | Monoamine oxidase type B | Monoamine oxidase type B (MAO B) | Monoamine oxidase type B (MAO B) | Monoamine oxidase type B (MAOB)
Type:Protein
Mol. Mass.:58768.76
Organism:Homo sapiens (Human)
Description:P27338
Residue:520
Sequence:
MSNKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSY
VGPTQNRILRLAKELGLETYKVNEVERLIHHVKGKSYPFRGPFPPVWNPITYLDHNNFWR
TMDDMGREIPSDAPWKAPLAEEWDNMTMKELLDKLCWTESAKQLATLFVNLCVTAETHEV
SALWFLWYVKQCGGTTRIISTTNGGQERKFVGGSGQVSERIMDLLGDRVKLERPVIYIDQ
TRENVLVETLNHEMYEAKYVISAIPPTLGMKIHFNPPLPMMRNQMITRVPLGSVIKCIVY
YKEPFWRKKDYCGTMIIDGEEAPVAYTLDDTKPEGNYAAIMGFILAHKARKLARLTKEER
LKKLCELYAKVLGSLEALEPVHYEEKNWCEEQYSGGCYTTYFPPGILTQYGRVLRQPVDR
IYFAGTETATHWSGYMEGAVEAGERAAREILHAMGKIPEDEIWQSEPESVDVPAQPITTT
FLERHLPSVPGLLRLIGLTTIFSATALGFLAHKRGLLVRV
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  Blast E-value cutoff:
BDBM10989
n/a
NameBDBM10989
Synonyms:(1R)-N-(prop-2-yn-1-yl)-2,3-dihydro-1H-inden-1-amine | CHEMBL887 | Rasagiline | US9034303, Rasagiline
TypeSmall organic molecule
Emp. Form.C12H13N
Mol. Mass.171.2383
SMILESC#CCN[C@@H]1CCc2ccccc12 |r|
Structure
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