| Reaction Details |
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 | Report a problem with these data |
| Target | Bcl-2-like protein 2 |
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| Ligand | BDBM50372180 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_464768 (CHEMBL930134) |
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| Ki | 2200±n/a nM |
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| Citation |  Wang, L; Kong, F; Kokoski, CL; Andrews, DW; Xing, C Development of dimeric modulators for anti-apoptotic Bcl-2 proteins. Bioorg Med Chem Lett18:236-40 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Bcl-2-like protein 2 |
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| Name: | Bcl-2-like protein 2 |
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| Synonyms: | Apoptosis regulator Bcl-W | B2CL2_HUMAN | BCL-W | BCL2L2 | BCLW | Bcl-2-like protein 2 | Bcl2-L-2 | KIAA0271 |
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| Type: | Protein |
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| Mol. Mass.: | 20742.61 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 193 |
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| Sequence: | MATPASAPDTRALVADFVGYKLRQKGYVCGAGPGEGPAADPLHQAMRAAGDEFETRFRRT
FSDLAAQLHVTPGSAQQRFTQVSDELFQGGPNWGRLVAFFVFGAALCAESVNKEMEPLVG
QVQEWMVAYLETQLADWIHSSGGWAEFTALYGDGALEEARRLREGNWASVRTVLTGAVAL
GALVTVGAFFASK
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| BDBM50372180 |
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| n/a |
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| Name | BDBM50372180 |
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| Synonyms: | CHEMBL270646 |
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| Type | Small organic molecule |
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| Emp. Form. | C42H36N2O9S4 |
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| Mol. Mass. | 841.003 |
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| SMILES | OC(=O)[C@H](Cc1ccccc1)N1C(=S)S\C(=C/c2ccc(OCCOCCOc3ccc(\C=C4/SC(=S)N([C@@H](Cc5ccccc5)C(O)=O)C4=O)cc3)cc2)C1=O |
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| Structure | 
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