| Reaction Details |
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 | Report a problem with these data |
| Target | D(1A) dopamine receptor |
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| Ligand | BDBM50373712 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_468366 (CHEMBL931950) |
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| Ki | 5100±n/a nM |
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| Citation |  Tietze, R; Löber, S; Hübner, H; Gmeiner, P; Kuwert, T; Prante, O Discovery of a dopamine D4 selective PET ligand candidate taking advantage of a click chemistry based REM linker. Bioorg Med Chem Lett18:983-8 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| D(1A) dopamine receptor |
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| Name: | D(1A) dopamine receptor |
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| Synonyms: | DRD1 | DRD1_PIG | Dopamine D1 receptor |
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| Type: | PROTEIN |
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| Mol. Mass.: | 49269.92 |
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| Organism: | Sus scrofa |
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| Description: | ChEMBL_1460140 |
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| Residue: | 446 |
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| Sequence: | MRTLNTSTMDGTGLVVERDFSFRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTN
FFVISLAVSDLLVAVLVMPWKAVAEIAGFWPFGSFCNIWVAFDIMCSTASILNLCVISVD
RYWAISSPFRYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTSPSDGNVTSLG
KTTHNCDSSLSRTYAISSSLISFYIPVAIMIVTYTRIYRIAQKQIRRISALERAAVHAKN
CQTTAGNGNPAECSQPESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFILNCMVPFCGS
GETKPFCIDSITFDVFVWFGWANSSLNPIIYAFNADFRKAFSTLLGCYRLCPTSTNAIET
VSINNNGAVVFSSHHEPRGSISKDCNLVYLIPHAVGSSEDLKKEEAGGIASPLEKLSPAL
SVILDYDTDVSLEKIQPITQNGQHPT
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| BDBM50373712 |
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| n/a |
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| Name | BDBM50373712 |
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| Synonyms: | CHEMBL255163 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H22ClFN2O |
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| Mol. Mass. | 348.842 |
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| SMILES | FCCOc1cccc(CN2CCN(CC2)c2ccc(Cl)cc2)c1 |
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| Structure | 
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