| Reaction Details |
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 | Report a problem with these data |
| Target | Muscarinic acetylcholine receptor M5 |
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| Ligand | BDBM50165008 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_468833 (CHEMBL932206) |
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| Ki | 2.2±n/a nM |
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| Citation |  Jones, LH; Randall, A; Napier, C; Trevethick, M; Sreckovic, S; Watson, J Design and synthesis of a fluorescent muscarinic antagonist. Bioorg Med Chem Lett18:825-7 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Muscarinic acetylcholine receptor M5 |
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| Name: | Muscarinic acetylcholine receptor M5 |
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| Synonyms: | ACM5_HUMAN | CHRM5 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 60102.35 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1517990 |
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| Residue: | 532 |
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| Sequence: | MEGDSYHNATTVNGTPVNHQPLERHRLWEVITIAAVTAVVSLITIVGNVLVMISFKVNSQ
LKTVNNYYLLSLACADLIIGIFSMNLYTTYILMGRWALGSLACDLWLALDYVASNASVMN
LLVISFDRYFSITRPLTYRAKRTPKRAGIMIGLAWLISFILWAPAILCWQYLVGKRTVPL
DECQIQFLSEPTITFGTAIAAFYIPVSVMTILYCRIYRETEKRTKDLADLQGSDSVTKAE
KRKPAHRALFRSCLRCPRPTLAQRERNQASWSSSRRSTSTTGKPSQATGPSANWAKAEQL
TTCSSYPSSEDEDKPATDPVLQVVYKSQGKESPGEEFSAEETEETFVKAETEKSDYDTPN
YLLSPAAAHRPKSQKCVAYKFRLVVKADGNQETNNGCHKVKIMPCPFPVAKEPSTKGLNP
NPSHQMTKRKRVVLVKERKAAQTLSAILLAFIITWTPYNIMVLVSTFCDKCVPVTLWHLG
YWLCYVNSTVNPICYALCNRTFRKTFKMLLLCRWKKKKVEEKLYWQGNSKLP
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| BDBM50165008 |
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| n/a |
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| Name | BDBM50165008 |
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| Synonyms: | (+)-(R)-2-(alpha-(2-(Diisopropylamino)ethyl)benzyl)-p-cresol | (+)-Tolterodine | 2-[(1R)-3-(diisopropylamino)-1-phenylpropyl]-4-methylphenol | CHEMBL1382 | TOLTERODINE |
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| Type | Small organic molecule |
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| Emp. Form. | C22H31NO |
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| Mol. Mass. | 325.4876 |
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| SMILES | CC(C)N(CC[C@H](c1ccccc1)c1cc(C)ccc1O)C(C)C |
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| Structure | 
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