Reaction Details |
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Target | Sigma non-opioid intracellular receptor 1 |
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Ligand | BDBM50374595 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_469590 (CHEMBL934063) |
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Ki | 4.9±n/a nM |
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Citation | Mésangeau, C; Narayanan, S; Green, AM; Shaikh, J; Kaushal, N; Viard, E; Xu, YT; Fishback, JA; Poupaert, JH; Matsumoto, RR; McCurdy, CR Conversion of a highly selective sigma-1 receptor-ligand to sigma-2 receptor preferring ligands with anticocaine activity. J Med Chem51:1482-6 (2008) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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Sigma non-opioid intracellular receptor 1 |
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Name: | Sigma non-opioid intracellular receptor 1 |
Synonyms: | Opioid receptor | Oprs1 | SGMR1_RAT | Sigma | Sigma non-opioid intracellular receptor 1 | Sigma opioid receptor | Sigma-1 | Sigmar1 |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 25266.54 |
Organism: | RAT |
Description: | Q9R0C9 |
Residue: | 223 |
Sequence: | MPWAVGRRWAWITLFLTIVAVLIQAVWLWLGTQSFVFQREEIAQLARQYAGLDHELAFSR
LIVELRRLHPGHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSHGHSGRY
WAEISDTIISGTFHQWREGTTKSEVYYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPS
TLAFALSDTIFSTQDFLTLFYTLRAYARGLRLELTTYLFGQDP
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BDBM50374595 |
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n/a |
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Name | BDBM50374595 |
Synonyms: | CHEMBL272854 | US9604926, Compound CM-372 | US9724435, Compound CM-372 |
Type | Small organic molecule |
Emp. Form. | C21H31N3OS |
Mol. Mass. | 373.555 |
SMILES | S=c1oc2ccccc2n1CCCCN1CCN(CC1)C1CCCCC1 |
Structure |
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