| Reaction Details |
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 | Report a problem with these data |
| Target | D(2) dopamine receptor |
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| Ligand | BDBM50374598 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_469598 (CHEMBL933157) |
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| Ki | 1041±n/a nM |
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| Citation |  Mésangeau, C; Narayanan, S; Green, AM; Shaikh, J; Kaushal, N; Viard, E; Xu, YT; Fishback, JA; Poupaert, JH; Matsumoto, RR; McCurdy, CR Conversion of a highly selective sigma-1 receptor-ligand to sigma-2 receptor preferring ligands with anticocaine activity. J Med Chem51:1482-6 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| D(2) dopamine receptor |
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| Name: | D(2) dopamine receptor |
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| Synonyms: | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2_RAT | Dopamine D2 receptor | Dopamine2-like | Drd2 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 50931.60 |
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| Organism: | Rattus norvegicus (rat) |
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| Description: | P61169 |
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| Residue: | 444 |
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| Sequence: | MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVS
REKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTA
SILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQN
ECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPL
KGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPP
SHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMS
RRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNS
AVNPIIYTTFNIEFRKAFMKILHC
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| BDBM50374598 |
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| n/a |
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| Name | BDBM50374598 |
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| Synonyms: | CHEMBL272603 | US9604926, Compound CM-156 | US9724435, Compound CM-156 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H31N3S2 |
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| Mol. Mass. | 389.621 |
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| SMILES | S=c1sc2ccccc2n1CCCCN1CCN(CC1)C1CCCCC1 |
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| Structure | 
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