| Reaction Details |
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 | Report a problem with these data |
| Target | C-X-C chemokine receptor type 3 |
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| Ligand | BDBM94647 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_470258 (CHEMBL950213) |
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| IC50 | 700±n/a nM |
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| Citation |  Hayes, ME; Breinlinger, EC; Wallace, GA; Grongsaard, P; Miao, W; McPherson, MJ; Stoffel, RH; Green, DW; Roth, GP Lead identification of 2-iminobenzimidazole antagonists of the chemokine receptor CXCR3. Bioorg Med Chem Lett18:2414-9 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| C-X-C chemokine receptor type 3 |
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| Name: | C-X-C chemokine receptor type 3 |
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| Synonyms: | AAO92295.1 | C-X-C chemokine receptor type 3 | C-X-C chemokine receptor type 3 (CXCR3) | C-X-C chemokine receptor type 3 (CXCR3A) | CXCR3 | CXCR3A | CXCR3_HUMAN | GPR9 | chemokine (C-X-C motif) receptor 3 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 40665.65 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 368 |
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| Sequence: | MVLEVSDHQVLNDAEVAALLENFSSSYDYGENESDSCCTSPPCPQDFSLNFDRAFLPALY
SLLFLLGLLGNGAVAAVLLSRRTALSSTDTFLLHLAVADTLLVLTLPLWAVDAAVQWVFG
SGLCKVAGALFNINFYAGALLLACISFDRYLNIVHATQLYRRGPPARVTLTCLAVWGLCL
LFALPDFIFLSAHHDERLNATHCQYNFPQVGRTALRVLQLVAGFLLPLLVMAYCYAHILA
VLLVSRGQRRLRAMRLVVVVVVAFALCWTPYHLVVLVDILMDLGALARNCGRESRVDVAK
SVTSGLGYMHCCLNPLLYAFVGVKFRERMWMLLLRLGCPNQRGLQRQPSSSRRDSSWSET
SEASYSGL
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| BDBM94647 |
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| n/a |
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| Name | BDBM94647 |
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| Synonyms: | 1-(4-chlorophenyl)-2-(2-imino-3-methyl-1-benzimidazolyl)ethanone;hydrobromide | 1-(4-chlorophenyl)-2-(2-imino-3-methyl-benzimidazol-1-yl)ethanone;hydrobromide | 1-(4-chlorophenyl)-2-(2-imino-3-methylbenzimidazol-1-yl)ethanone;hydrobromide | 2-(2-azanylidene-3-methyl-benzimidazol-1-yl)-1-(4-chlorophenyl)ethanone;hydrobromide | CHEMBL272282 | MLS-0471929.0001 | cid_44889184 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H14ClN3O |
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| Mol. Mass. | 299.755 |
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| SMILES | Cn1c2ccccc2n(CC(=O)c2ccc(Cl)cc2)c1=N |
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| Structure | 
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