| Reaction Details |
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 | Report a problem with these data |
| Target | C-X-C chemokine receptor type 3 |
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| Ligand | BDBM50375125 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_470260 (CHEMBL950215) |
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| IC50 | 1800±n/a nM |
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| Citation |  Hayes, ME; Breinlinger, EC; Wallace, GA; Grongsaard, P; Miao, W; McPherson, MJ; Stoffel, RH; Green, DW; Roth, GP Lead identification of 2-iminobenzimidazole antagonists of the chemokine receptor CXCR3. Bioorg Med Chem Lett18:2414-9 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| C-X-C chemokine receptor type 3 |
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| Name: | C-X-C chemokine receptor type 3 |
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| Synonyms: | CXCR3_MOUSE | Cmkar3 | Cxcr3 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 41020.84 |
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| Organism: | Mus musculus |
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| Description: | ChEMBL_560734 |
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| Residue: | 367 |
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| Sequence: | MYLEVSERQVLDASDFAFLLENSTSPYDYGENESDFSDSPPCPQDFSLNFDRTFLPALYS
LLFLLGLLGNGAVAAVLLSQRTALSSTDTFLLHLAVADVLLVLTLPLWAVDAAVQWVFGP
GLCKVAGALFNINFYAGAFLLACISFDRYLSIVHATQIYRRDPRVRVALTCIVVWGLCLL
FALPDFIYLSANYDQRLNATHCQYNFPQVGRTALRVLQLVAGFLLPLLVMAYCYAHILAV
LLVSRGQRRFRAMRLVVVVVAAFAVCWTPYHLVVLVDILMDVGVLARNCGRESHVDVAKS
VTSGMGYMHCCLNPLLYAFVGVKFREQMWMLFTRLGRSDQRGPQRQPSSSRRESSWSETT
EASYLGL
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| BDBM50375125 |
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| n/a |
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| Name | BDBM50375125 |
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| Synonyms: | CHEMBL256891 |
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| Type | Small organic molecule |
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| Emp. Form. | C29H31ClN4O2 |
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| Mol. Mass. | 503.035 |
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| SMILES | CCc1cccc2n(CC(=O)c3ccc(Cl)cc3)c(=N)n(CCCN(C)C(=O)Cc3ccccc3)c12 |
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| Structure | 
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