| Reaction Details |
|---|
 | Report a problem with these data |
| Target | C-X-C chemokine receptor type 3 |
|---|
| Ligand | BDBM50375126 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_470260 (CHEMBL950215) |
|---|
| IC50 | 1400±n/a nM |
|---|
| Citation |  Hayes, ME; Breinlinger, EC; Wallace, GA; Grongsaard, P; Miao, W; McPherson, MJ; Stoffel, RH; Green, DW; Roth, GP Lead identification of 2-iminobenzimidazole antagonists of the chemokine receptor CXCR3. Bioorg Med Chem Lett18:2414-9 (2008) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| C-X-C chemokine receptor type 3 |
|---|
| Name: | C-X-C chemokine receptor type 3 |
|---|
| Synonyms: | CXCR3_MOUSE | Cmkar3 | Cxcr3 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 41020.84 |
|---|
| Organism: | Mus musculus |
|---|
| Description: | ChEMBL_560734 |
|---|
| Residue: | 367 |
|---|
| Sequence: | MYLEVSERQVLDASDFAFLLENSTSPYDYGENESDFSDSPPCPQDFSLNFDRTFLPALYS
LLFLLGLLGNGAVAAVLLSQRTALSSTDTFLLHLAVADVLLVLTLPLWAVDAAVQWVFGP
GLCKVAGALFNINFYAGAFLLACISFDRYLSIVHATQIYRRDPRVRVALTCIVVWGLCLL
FALPDFIYLSANYDQRLNATHCQYNFPQVGRTALRVLQLVAGFLLPLLVMAYCYAHILAV
LLVSRGQRRFRAMRLVVVVVAAFAVCWTPYHLVVLVDILMDVGVLARNCGRESHVDVAKS
VTSGMGYMHCCLNPLLYAFVGVKFREQMWMLFTRLGRSDQRGPQRQPSSSRRESSWSETT
EASYLGL
|
|
|
|---|
| BDBM50375126 |
|---|
| n/a |
|---|
| Name | BDBM50375126 |
|---|
| Synonyms: | CHEMBL255583 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C27H26Cl2N4O2 |
|---|
| Mol. Mass. | 509.427 |
|---|
| SMILES | CN(CCCn1c2c(Cl)cccc2n(CC(=O)c2ccc(Cl)cc2)c1=N)C(=O)Cc1ccccc1 |
|---|
| Structure | 
|
|---|
Search and Browse
