| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Thyroid hormone receptor beta |
|---|
| Ligand | BDBM50375343 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_471201 (CHEMBL939180) |
|---|
| Kd | 36±n/a nM |
|---|
| Citation |  Ocasio, CA; Scanlan, TS Characterization of thyroid hormone receptor alpha (TRalpha)-specific analogs with varying inner- and outer-ring substituents. Bioorg Med Chem16:762-70 (2008) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Thyroid hormone receptor beta |
|---|
| Name: | Thyroid hormone receptor beta |
|---|
| Synonyms: | ERBA2 | NR1A2 | Nuclear receptor subfamily 1 group A member 2 | THB_HUMAN | THR1 | THRB | c-erbA-2 | c-erbA-beta |
|---|
| Type: | Receptor |
|---|
| Mol. Mass.: | 52793.62 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Recombinant hThR was obtained from nuclear extracts from SF9 cells infected with baculovirus vectors encoding for ThRbeta 1. |
|---|
| Residue: | 461 |
|---|
| Sequence: | MTPNSMTENGLTAWDKPKHCPDREHDWKLVGMSEACLHRKSHSERRSTLKNEQSSPHLIQ
TTWTSSIFHLDHDDVNDQSVSSAQTFQTEEKKCKGYIPSYLDKDELCVVCGDKATGYHYR
CITCEGCKGFFRRTIQKNLHPSYSCKYEGKCVIDKVTRNQCQECRFKKCIYVGMATDLVL
DDSKRLAKRKLIEENREKRRREELQKSIGHKPEPTDEEWELIKTVTEAHVATNAQGSHWK
QKRKFLPEDIGQAPIVNAPEGGKVDLEAFSHFTKIITPAITRVVDFAKKLPMFCELPCED
QIILLKGCCMEIMSLRAAVRYDPESETLTLNGEMAVTRGQLKNGGLGVVSDAIFDLGMSL
SSFNLDDTEVALLQAVLLMSSDRPGLACVERIEKYQDSFLLAFEHYINYRKHHVTHFWPK
LLMKVTDLRMIGACHASRFLHMKVECPTELFPPLFLEVFED
|
|
|
|---|
| BDBM50375343 |
|---|
| n/a |
|---|
| Name | BDBM50375343 |
|---|
| Synonyms: | CHEMBL259096 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C16H11I3N2O4 |
|---|
| Mol. Mass. | 675.983 |
|---|
| SMILES | Oc1[nH]c(=O)[nH]c1Cc1cc(I)c(Oc2ccc(O)c(I)c2)c(I)c1 |
|---|
| Structure | 
|
|---|
Search and Browse
